INT39390

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Context Info
Confidence 0.43
First Reported 1986
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 8
Total Number 8
Disease Relevance 9.83
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Hdl2 (Mus musculus)
Pain Link Frequency Relevance Heat
Angina 10 81.24 Quite High
corticosteroid 1 78.16 Quite High
withdrawal 6 5.00 Very Low Very Low Very Low
transdermal 6 5.00 Very Low Very Low Very Low
Dismenorea 4 5.00 Very Low Very Low Very Low
cva 4 5.00 Very Low Very Low Very Low
headache 4 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
Migraine 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 820 100.00 Very High Very High Very High
Obesity 4 98.84 Very High Very High Very High
Nicotine Addiction 7 98.48 Very High Very High Very High
Coronary Artery Disease 62 97.48 Very High Very High Very High
Cv General 3 Under Development 9 81.24 Quite High
Angina 1 80.44 Quite High
Myocardial Infarction 6 78.84 Quite High
Cardiovascular Disease 15 73.56 Quite High
Congenital Anomalies 6 66.60 Quite High
Insulin Resistance 1 53.28 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The reductions of HDL2 and HDL3 were significant as well in smoking as in nonsmoking CAD patients and both in patients with and without beta-adrenoceptor blocking drugs.
Negative_regulation (reductions) of HDL2 associated with coronary artery disease and nicotine addiction
1) Confidence 0.43 Published 1986 Journal Atherosclerosis Section Abstract Doc Link 3964340 Disease Relevance 1.02 Pain Relevance 0.07
The decrease of HDL2-C and HDL3-PL were significant also after allowance for the influences of obesity and triglyceride level.
Negative_regulation (decrease) of HDL2 associated with obesity
2) Confidence 0.43 Published 1986 Journal Atherosclerosis Section Abstract Doc Link 3964340 Disease Relevance 1.03 Pain Relevance 0.08
Proportionally there was a greater reduction of C and PL in HDL2 than in HDL3.
Negative_regulation (reduction) of HDL2
3) Confidence 0.43 Published 1986 Journal Atherosclerosis Section Abstract Doc Link 3964340 Disease Relevance 1.03 Pain Relevance 0.08
Gradient gel electrophoresis of the total HDL demonstrated that the coronary patients had a significantly decreased concentration of the large HDL particles, HDL2b, of mean diameter 10.57 nm and a higher concentration of the smaller-sized HDL3, especially HDL3c, of mean diameter 7.62 nm.
Negative_regulation (decreased) of HDL2b associated with disorder of lipid metabolism
4) Confidence 0.21 Published 1993 Journal Clin. Chim. Acta Section Abstract Doc Link 8111962 Disease Relevance 1.06 Pain Relevance 0.08
Furthermore, it is interesting to note that there was a significant reduction of the HDL2b/pre?
Negative_regulation (reduction) of HDL2b
5) Confidence 0.15 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2920871 Disease Relevance 1.89 Pain Relevance 0
Specific HDL subclasses are involved in certain steps of RCT, and a low HDL2b/pre?
Negative_regulation (pre) of HDL2b associated with disorder of lipid metabolism
6) Confidence 0.15 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2920871 Disease Relevance 1.66 Pain Relevance 0
The opposite of this pattern was observed in the borderline LDL-C (3.36-4.11 mmol/L) and desirable LDL-C (< 3.34 mmol/L) groups, and the subjects in these two groups had significantly higher HDL2b/pre?
Negative_regulation (had) of HDL2b
7) Confidence 0.15 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2920871 Disease Relevance 1.53 Pain Relevance 0
In contrast to a decrease in HDL, HDL2, and HDL3 levels in the COC group, HDL2 increased in NuvaRing group.
Negative_regulation (decrease) of HDL2 associated with disorder of lipid metabolism
8) Confidence 0.13 Published 2010 Journal International Journal of Women's Health Section Body Doc Link PMC2990910 Disease Relevance 0.62 Pain Relevance 0.04

General Comments

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