INT39414

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Context Info
Confidence 0.59
First Reported 1985
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 37
Total Number 40
Disease Relevance 14.07
Pain Relevance 2.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (SNRPB) nucleoplasm (SNRPB) mRNA processing (SNRPB)
nucleus (SNRPB) cytoplasm (SNRPB)
Anatomy Link Frequency
plasma 4
blood 2
lamina 2
skin 2
upper 2
SNRPB (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 9 100.00 Very High Very High Very High
GABAergic 3 100.00 Very High Very High Very High
Inflammatory marker 8 99.64 Very High Very High Very High
Inflammation 223 99.24 Very High Very High Very High
Bile 1 97.44 Very High Very High Very High
antagonist 6 96.72 Very High Very High Very High
agonist 11 96.12 Very High Very High Very High
cINOD 57 93.92 High High
excitatory amino acid 1 93.12 High High
psoriasis 19 87.04 High High
Disease Link Frequency Relevance Heat
Blister 266 99.96 Very High Very High Very High
Nicotine Addiction 17 99.84 Very High Very High Very High
Diabetes Mellitus 41 99.48 Very High Very High Very High
INFLAMMATION 439 99.36 Very High Very High Very High
Sprains And Strains 6 99.28 Very High Very High Very High
Corneal Edema 38 99.24 Very High Very High Very High
Atherosclerosis 153 99.08 Very High Very High Very High
Diabetes Mellitus-type I 3 98.64 Very High Very High Very High
Disorders Of The Lacrimal System 24 96.84 Very High Very High Very High
Injury 334 95.36 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Similar to human spines, site-specific HVLA-SM produced regional cat FJC strains at distant motion segments.
Gene_expression (produced) of HVLA-SM in FJC associated with sprains and strains
1) Confidence 0.59 Published 2010 Journal J Biomech Eng Section Abstract Doc Link 20590286 Disease Relevance 0.53 Pain Relevance 0.03
Plasma SM levels are related to atherogenic lipoprotein aggregation, which is the initial step in the development of atherosclerosis [17].
Gene_expression (levels) of SM in Plasma associated with atherosclerosis
2) Confidence 0.31 Published 2006 Journal Nutr Metab (Lond) Section Body Doc Link PMC1360085 Disease Relevance 1.06 Pain Relevance 0.14
However, plasma SM levels did not correlate with Hs-CRP in our study (Table 2).
Gene_expression (levels) of SM in plasma
3) Confidence 0.31 Published 2006 Journal Nutr Metab (Lond) Section Body Doc Link PMC1360085 Disease Relevance 1.04 Pain Relevance 0.14
Plasma SM levels were measured as described previously [19].
Gene_expression (levels) of SM in Plasma
4) Confidence 0.27 Published 2006 Journal Nutr Metab (Lond) Section Body Doc Link PMC1360085 Disease Relevance 0.29 Pain Relevance 0
We found a trend for higher plasma SM concentrations in smokers.
Gene_expression (concentrations) of SM in plasma associated with nicotine addiction
5) Confidence 0.27 Published 2006 Journal Nutr Metab (Lond) Section Body Doc Link PMC1360085 Disease Relevance 0.77 Pain Relevance 0.08
Recent studies have suggested a partial block in somatomedin (SM) production or growth hormone (GH) action in IDDM.
Gene_expression (production) of SM associated with diabetes mellitus-type i
6) Confidence 0.18 Published 1985 Journal Diabetes Section Abstract Doc Link 3967801 Disease Relevance 0.33 Pain Relevance 0.14
Thus, a first manner to implement CPM would be:

(23)r(SM(?

Gene_expression (would) of SM
7) Confidence 0.18 Published 2007 Journal Frontiers in Neurorobotics Section Body Doc Link PMC2533589 Disease Relevance 0 Pain Relevance 0
where SM(?
Gene_expression (where) of SM
8) Confidence 0.18 Published 2007 Journal Frontiers in Neurorobotics Section Body Doc Link PMC2533589 Disease Relevance 0 Pain Relevance 0
Our data indicate a blunted SM response to hGH in group B diabetic subjects; this defect in SM generation is apparently not present in group A subjects.
Gene_expression (generation) of SM associated with diabetes mellitus
9) Confidence 0.16 Published 1985 Journal Diabetes Section Abstract Doc Link 3967801 Disease Relevance 0.35 Pain Relevance 0.13
The basal SM levels of both groups were normal for age.
Gene_expression (levels) of SM
10) Confidence 0.12 Published 1985 Journal Diabetes Section Abstract Doc Link 3967801 Disease Relevance 0.37 Pain Relevance 0.16
Protein expression was assessed using a two-dimensional gel system instead of an LC-MS platform, so that a visual picture of similarities and differences in types and amounts of proteins expressed between COD could be obtained.
Gene_expression (expressed) of COD
11) Confidence 0.08 Published 2010 Journal BMC Genomics Section Body Doc Link PMC3014982 Disease Relevance 0 Pain Relevance 0
Lassen) cultivars representative of the two market classes were selected for this study to represent the Middle American and Andean COD, respectively.
Gene_expression (represent) of COD
12) Confidence 0.08 Published 2010 Journal BMC Genomics Section Body Doc Link PMC3014982 Disease Relevance 0.08 Pain Relevance 0
However we caution the reader that the purpose of this experimental approach was primarily the qualitative evaluation of distinguishing differences in transcript, protein, and/or metabolite expression between COD.
Gene_expression (expression) of COD
13) Confidence 0.07 Published 2010 Journal BMC Genomics Section Body Doc Link PMC3014982 Disease Relevance 0 Pain Relevance 0
Uterus SMCs also have especially high expression levels of many genes that encode the contractile machinery of SMCs, including tropomyosin 1 and 2, calponin, caldesmon 1, SM-?
Gene_expression (expression) of SM in Uterus
14) Confidence 0.05 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1994710 Disease Relevance 0.08 Pain Relevance 0.21
Beyond the viscera, SM is also present in a variety of anatomical locations, such as the hair follicles, irises, and lacrimal ducts.
Gene_expression (present) of SM in irises associated with disorders of the lacrimal system
15) Confidence 0.04 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1994710 Disease Relevance 0.19 Pain Relevance 0
These genes are widely considered as cell-type lineage markers for all SMCs; indeed, expression of SM-?
Gene_expression (expression) of SM
16) Confidence 0.04 Published 2007 Journal PLoS Genetics Section Body Doc Link PMC1994710 Disease Relevance 0.06 Pain Relevance 0.18
These adducts were visualized using the lateral flow technique to form a clearly visible line.103 The SMD was able to detect SM vapor released from a 20 ?
Gene_expression (vapor) of SM in lateral
17) Confidence 0.04 Published 2008 Journal Eplasty Section Body Doc Link PMC2431646 Disease Relevance 0 Pain Relevance 0
Indeed, it has been shown recently that the adduct levels of SM to hemoglobin in guinea pigs and marmosets increase over several days.14 A similar behavior may be observed in humans, as unhydrolyzed agent has been found in fatty tissues of an SM victim.15 In addition, blood samples taken 3 to 4 weeks after exposure showed substantial SM N7-guanine adducts in the DNA.16 This is rather surprising, as DNA adducts are more or less effectively repaired within 24 hours.17
Gene_expression (levels) of SM in blood
18) Confidence 0.04 Published 2008 Journal Eplasty Section Body Doc Link PMC2431646 Disease Relevance 0.14 Pain Relevance 0
The prototype SMD has been shown to detect SM on skin and in the environment.
Gene_expression (detect) of SM in skin
19) Confidence 0.03 Published 2008 Journal Eplasty Section Body Doc Link PMC2431646 Disease Relevance 0.42 Pain Relevance 0.04
Thus, high SM concentrations can rapidly deplete the intracellular glutathione levels, resulting in the enhanced production of reactive oxygen species.44 Consequently, pretreatment of cells with various antioxidants does not only enhance cell survival44,45 but antioxidants have also been shown to be most effective in treating SM lung injury in animal models.46–48
Gene_expression (concentrations) of SM in lung associated with lung injury
20) Confidence 0.03 Published 2008 Journal Eplasty Section Body Doc Link PMC2431646 Disease Relevance 0.09 Pain Relevance 0

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