INT39462

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Context Info
Confidence 0.44
First Reported 1985
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 3.31
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Tg) extracellular region (Tg) Golgi apparatus (Tg)
endoplasmic reticulum (Tg)
Anatomy Link Frequency
thyroid 2
Tg (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 7 98.48 Very High Very High Very High
Abeta 3 92.20 High High
corticosteroid 1 85.92 High High
palliative 3 76.20 Quite High
Enkephalin 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Thyroid Disease 2 99.90 Very High Very High Very High
Thyroid Neoplasm 13 99.48 Very High Very High Very High
Thyroiditis 3 98.12 Very High Very High Very High
Hemorrhage 2 97.28 Very High Very High Very High
Pain 3 96.76 Very High Very High Very High
Fever 1 96.40 Very High Very High Very High
Disease 5 95.52 Very High Very High Very High
Suppurative Thyroiditis 7 91.68 High High
Bacterial Infection 1 90.56 High High
Myeloid Leukemia 1 90.24 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Serum thyroglobulin (Tg) levels were elevated in 92% of 38 patients with subacute "painful" thyroiditis in the early stage, independent of the extent of the disease and thyroid hormone concentrations.
Positive_regulation (elevated) of Gene_expression (levels) of thyroglobulin in thyroid associated with pain, thyroiditis and disease
1) Confidence 0.44 Published 1985 Journal Arch. Intern. Med. Section Abstract Doc Link 3977482 Disease Relevance 0.33 Pain Relevance 0.22
We observed a massive increase of thyroglobulin (Tg) concentrations in cases of DTC that started 36-48 h after SETA and did not occur in cases of ATC.
Positive_regulation (increase) of Gene_expression (concentrations) of thyroglobulin associated with thyroid neoplasm
2) Confidence 0.12 Published 2007 Journal Endocr. Relat. Cancer Section Abstract Doc Link 17914113 Disease Relevance 1.31 Pain Relevance 0.29
Laboratory tests showed hyperthyroidism and elevated levels of thyroglobulin and C-reactive protein.
Positive_regulation (elevated) of Gene_expression (levels) of thyroglobulin associated with thyroid disease
3) Confidence 0.09 Published 2002 Journal Pediatr Hematol Oncol Section Abstract Doc Link 12051591 Disease Relevance 1.34 Pain Relevance 0.10
C100/TGN co-transfected with mt PS2 increased levels or ratios of intracellular as well as secreted Abeta42 at similar levels to those with C100 without signals (C100/WT), whereas C100/ER yielded a negligible level of Abeta, which was not affected by co-transfection of mt PS2.
Positive_regulation (co-transfected) of Gene_expression (co-transfected) of TGN associated with abeta
4) Confidence 0.04 Published 2001 Journal J. Biol. Chem. Section Abstract Doc Link 11283011 Disease Relevance 0.33 Pain Relevance 0.11

General Comments

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