INT39640

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Context Info
Confidence 0.25
First Reported 1985
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.13
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Plg) extracellular space (Plg) extracellular region (Plg)
Anatomy Link Frequency
blood 2
liver 2
Plg (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Migraine 5 80.16 Quite High
cytokine 2 70.44 Quite High
Inflammation 2 60.84 Quite High
chemokine 2 59.40 Quite High
anesthesia 1 55.24 Quite High
headache 1 31.08 Quite Low
Disease Link Frequency Relevance Heat
Thrombophilia 1 98.60 Very High Very High Very High
Hypoxia 4 95.24 Very High Very High Very High
Cerebral Toxoplasmosis 4 89.60 High High
Congenital Anomalies 1 85.40 High High
Patent Foramen Ovale 6 82.32 Quite High
Headache 6 80.16 Quite High
Adhesions 1 62.40 Quite High
INFLAMMATION 2 60.84 Quite High
Atrial Heart Septal Defects 1 45.08 Quite Low
Toxoplasmosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Synthesis of plasminogen in this group of perfusions was progressively decreased as the concentration of DES administered to the rat liver donor increased.
Negative_regulation (decreased) of Gene_expression (Synthesis) of plasminogen in liver
1) Confidence 0.25 Published 1985 Journal Blood Section Abstract Doc Link 4016277 Disease Relevance 0 Pain Relevance 0.06
In addition, hypoxia may participate in paradoxical microembolism because arterial oxygen desaturation enhances expression of plasminogen activator inhibitor-1, an important factor which suppresses fibrinolysis, and this effect may be further amplified by a decreased expression of plasminogen activators, finally causing blood hypercoagulability and paradoxical microembolism.
Negative_regulation (decreased) of Gene_expression (expression) of plasminogen in blood associated with thrombophilia and hypoxia
2) Confidence 0.02 Published 2010 Journal Int. J. Neurosci. Section Abstract Doc Link 20199198 Disease Relevance 1.13 Pain Relevance 0.33

General Comments

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