INT39678

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Context Info
Confidence 0.17
First Reported 1985
Last Reported 1985
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.34
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (Atrn) extracellular space (Atrn) extracellular region (Atrn)
plasma membrane (Atrn) molecular_function (Atrn) cytoplasm (Atrn)
Anatomy Link Frequency
plasma 2
Atrn (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 3 93.28 High High
Disease Link Frequency Relevance Heat
Hepatotoxicity 1 99.88 Very High Very High Very High
Injury 2 94.96 High High
Necrosis 1 94.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Alkylation of sites on the plasma membrane may be a key chemical-macromolecule interaction in drug-induced liver necrosis, and inhibition of plasma membrane Ca2+ regulation may provide a connecting link between the alkylation hypothesis and the perturbed Ca2+ homeostasis hypothesis of lethal cell injury.
Negative_regulation (inhibition) of Regulation (regulation) of membrane in plasma associated with injury and hepatotoxicity
1) Confidence 0.17 Published 1985 Journal Mol. Pharmacol. Section Abstract Doc Link 4021997 Disease Relevance 0.34 Pain Relevance 0.25

General Comments

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