INT39703

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Context Info
Confidence 0.39
First Reported 1983
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 0.39
Pain Relevance 1.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Ccl4) extracellular region (Ccl4)
Ccl4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Paracetamol 13 96.76 Very High Very High Very High
Bile 7 95.84 Very High Very High Very High
Inflammation 21 5.00 Very Low Very Low Very Low
Inflammatory mediators 6 5.00 Very Low Very Low Very Low
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
alcohol 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Fistula 1 92.32 High High
Hepatotoxicity 28 88.84 High High
Body Weight 3 77.92 Quite High
Toxicity 9 67.40 Quite High
Stress 30 63.80 Quite High
Apoptosis 57 5.00 Very Low Very Low Very Low
INFLAMMATION 27 5.00 Very Low Very Low Very Low
Death 24 5.00 Very Low Very Low Very Low
Injury 24 5.00 Very Low Very Low Very Low
Disease 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Effect of the administration of CCl4 with and without the prior administration of natansnin on lipid peroxide level is shown in Figure 1.
Regulation (Effect) of CCl4
1) Confidence 0.39 Published 2010 Journal BMC Pharmacol Section Body Doc Link PMC2967507 Disease Relevance 0.13 Pain Relevance 0
Effect of CCl4 with and without the prior administration of natansnin on levels of glutathione (both oxidized and reduced) is shown in Figure 2.
Regulation (Effect) of CCl4
2) Confidence 0.39 Published 2010 Journal BMC Pharmacol Section Body Doc Link PMC2967507 Disease Relevance 0.08 Pain Relevance 0
The activity of superoxide dismutase decreased in homogenate, mitochondrial fragment and mitochondria by 47 (1.51 ± 0.11 units/mg protein), 52 (1.48 ± 0.10 units/mg protein) and 57 (2.10 ± 0.25 units/mg protein) % respectively due to the effect of CCl4, when compared to normal rats (received only mineral oil).
Regulation (effect) of CCl4
3) Confidence 0.23 Published 2010 Journal BMC Pharmacol Section Body Doc Link PMC2967507 Disease Relevance 0 Pain Relevance 0
These observations are discussed with respect to the effects of phenobarbital, phorone and CCl4 on microsomal and cytosolic GSH-dependent enzymes involved in the metabolism of AA.
Regulation (effects) of CCl4 associated with paracetamol
4) Confidence 0.23 Published 1985 Journal Arch Int Pharmacodyn Ther Section Abstract Doc Link 4026465 Disease Relevance 0.09 Pain Relevance 0.83
Effects of phenobarbital, GSH-depletors, CCl4 and ethanol on the biliary efflux of glutathione in rats.
Regulation (Effects) of CCl4
5) Confidence 0.20 Published 1983 Journal Arch Int Pharmacodyn Ther Section Title Doc Link 6667071 Disease Relevance 0.09 Pain Relevance 0.25

General Comments

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