INT3971

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Context Info
Confidence 0.70
First Reported 1975
Last Reported 2011
Negated 8
Speculated 3
Reported most in Abstract
Documents 175
Total Number 180
Disease Relevance 98.46
Pain Relevance 36.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Alb) extracellular space (Alb) extracellular region (Alb)
enzyme binding (Alb) DNA binding (Alb) protein complex (Alb)
Anatomy Link Frequency
plasma 13
urine 6
blood 5
liver 4
body 3
Alb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 254 100.00 Very High Very High Very High
halothane 245 100.00 Very High Very High Very High
qutenza 81 100.00 Very High Very High Very High
Inflammatory response 46 100.00 Very High Very High Very High
ischemia 22 100.00 Very High Very High Very High
Glutamate 1 100.00 Very High Very High Very High
cINOD 57 99.98 Very High Very High Very High
bDMF 9 99.98 Very High Very High Very High
methadone 6 99.92 Very High Very High Very High
Morphine 15 99.86 Very High Very High Very High
Disease Link Frequency Relevance Heat
Diabetes Mellitus 660 100.00 Very High Very High Very High
INFLAMMATION 296 100.00 Very High Very High Very High
Anxiety Disorder 117 100.00 Very High Very High Very High
Body Weight 80 100.00 Very High Very High Very High
Cv Unclassified Under Development 46 100.00 Very High Very High Very High
Disorder Of Lipid Metabolism 37 100.00 Very High Very High Very High
Proteinuria 29 100.00 Very High Very High Very High
Burns 25 100.00 Very High Very High Very High
Cyst 2 100.00 Very High Very High Very High
Coagulation Disorder 1 100.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results demonstrate that pentobarbital anesthesia when given into the peritoneal cavity causes a significant increase in albumin leakage in the abdominal region.
Positive_regulation (increase) of albumin in peritoneal cavity associated with anesthesia
1) Confidence 0.70 Published 1990 Journal Proc. Soc. Exp. Biol. Med. Section Abstract Doc Link 2399251 Disease Relevance 0 Pain Relevance 0.34
The inhibitory effect of naloxone, methadone, or naloxone plus methadone on albumin accumulation in the culture medium was greater than the drug-induced reduction of protein synthesis.
Positive_regulation (accumulation) of albumin associated with narcan and methadone
2) Confidence 0.70 Published 1984 Journal Exp. Cell Biol. Section Abstract Doc Link 6489584 Disease Relevance 0.33 Pain Relevance 1.10
Two months after capsaicin treatment a significant increase in albumin extravasation was found in the lower (P < 0.005), but not in the upper (5-8 cm from the anus) part of the colon as compared to the sham-operated control.
Positive_regulation (increase) of albumin in upper associated with qutenza
3) Confidence 0.70 Published 1997 Journal J. Physiol. Paris Section Abstract Doc Link 9403785 Disease Relevance 0.22 Pain Relevance 0.44
RESULTS: The LPS group demonstrated statistically significant increase in both effusion volume and albumin concentration compared with saline solution.
Positive_regulation (increase) of albumin
4) Confidence 0.70 Published 2006 Journal Otolaryngol Head Neck Surg Section Body Doc Link 17011422 Disease Relevance 0.17 Pain Relevance 0
After 14-30 days, increase of the albumin and decrease of the alpha1-, gammay-globulins were detected.
Positive_regulation (increase) of albumin
5) Confidence 0.70 Published 2005 Journal Ross Fiziol Zh Im I M Sechenova Section Abstract Doc Link 16206619 Disease Relevance 0 Pain Relevance 0.35
In the second group of experiments, 2 microl of cytochalasin D injected subdermally into rats with intact circulation increased the total tissue water (TTW) and albumin extravasation rate (E(ALB)) by 0.7 +/- 0.2 and 0.4 +/- 0.3 ml/g dry wt, respectively (P < 0.05 compared with vehicle).
Positive_regulation (increased) of albumin
6) Confidence 0.69 Published 2001 Journal Am. J. Physiol. Heart Circ. Physiol. Section Abstract Doc Link 11406462 Disease Relevance 0.21 Pain Relevance 0.10
During the initial period (up to seven days), "acute-type" changes in protein content were seen; at 11-30 days, there were chronic increases in the albumin level with decreases in alpha(1), alpha(2), and gamma globulins.
Positive_regulation (increases) of albumin
7) Confidence 0.69 Published 2006 Journal Neurosci. Behav. Physiol. Section Abstract Doc Link 16841154 Disease Relevance 0.18 Pain Relevance 0.55
Both NSAIDs induced the recruitment of adherent and emigrated leukocytes with temporally related increases in albumin leakage.
Positive_regulation (increases) of albumin in leukocytes associated with cinod
8) Confidence 0.69 Published 1996 Journal Am. J. Physiol. Section Abstract Doc Link 8779980 Disease Relevance 0.42 Pain Relevance 0.60
The time-course of serum 17beta-estradiol and progesterone released from these capsules in the OVX rat is characterized by an initial increase in serum hormone levels followed by a decline and then an apparent steady-state that persists from 7 to 24 days postimplant.
Positive_regulation (increase) of serum hormone in capsules
9) Confidence 0.68 Published 2005 Journal J Pain Section Abstract Doc Link 16326369 Disease Relevance 0 Pain Relevance 0.05
These data indicate that in streptozotocin diabetes there is an expansion of the inducible aortic histamine pool, and that this expansion is intimately related to the increased aortic albumin accumulation.
Positive_regulation (accumulation) of albumin associated with experimental diabetes mellitus
10) Confidence 0.68 Published 1983 Journal Arteriosclerosis Section Abstract Doc Link 6651615 Disease Relevance 0.81 Pain Relevance 0.05
Examination of cerebrospinal fluid revealed lymphocytic pleocytosis and increased albumin and lactate concentrations.
Positive_regulation (increased) of albumin in cerebrospinal fluid
11) Confidence 0.68 Published 2010 Journal Dtsch. Med. Wochenschr. Section Body Doc Link 20648409 Disease Relevance 0.09 Pain Relevance 0
In NAR rats transplanted with normal hepatocytes, there was a significant (P < 0.003) and sustained (12 weeks) increase in plasma albumin levels.
Positive_regulation (increase) of albumin in plasma
12) Confidence 0.68 Published 1993 Journal Transplantation Section Abstract Doc Link 8516804 Disease Relevance 0 Pain Relevance 0.19
Reduction of joint pains as well as increase of mobility and decrease of swelling of several joints were observed. the clinical signs of reduced inflammation were accompanied biochemically by reduction of serum immunoglobulins and an increase of serum albumin.
Positive_regulation (increase) of serum albumin in joint associated with pressure and volume under development, arthralgia and inflammation
13) Confidence 0.67 Published 1980 Journal Br. J. Dermatol. Section Abstract Doc Link 7002197 Disease Relevance 0.71 Pain Relevance 0.27
Administration of the NO synthase inhibitors, N(G)-nitro-L-arginine methyl ester (1-5 mg kg(-1), s.c.) and N(G)-monomethyl-L-arginine (12.5-50 mg kg(-1), s.c.), provoked a further substantial elevation of gastrointestinal albumin extravasation in the surgically manipulated rat, but not in control rats.
Positive_regulation (elevation) of albumin
14) Confidence 0.67 Published 1999 Journal Eur. J. Pharmacol. Section Abstract Doc Link 10443577 Disease Relevance 0 Pain Relevance 0
The lower dose induced the development of an immediate oedema associated with a progressive accumulation of 125I-labelled albumin in the paws.
Positive_regulation (accumulation) of albumin associated with pressure and volume under development
15) Confidence 0.67 Published 1999 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 10208309 Disease Relevance 0.49 Pain Relevance 0.40
The increases in urinary albumin and protein after eight weeks of treatment were significantly inhibited by prolonged treatment with PPE.
Positive_regulation (increases) of albumin
16) Confidence 0.67 Published 2008 Journal Ren Fail Section Abstract Doc Link 18350451 Disease Relevance 1.76 Pain Relevance 0.10
Inhibition of aortic histamine synthesis by alpha-hydrazinohistidine inhibits increased aortic albumin accumulation in experimental diabetes in the rat.
Positive_regulation (accumulation) of aortic albumin associated with diabetes mellitus
17) Confidence 0.61 Published 1985 Journal Diabetologia Section Title Doc Link 4018454 Disease Relevance 0.62 Pain Relevance 0.09
Aortic albumin accumulation was measured by quantification of aortic uptake of fluorescein isothiocyanate conjugated to rat serum albumin injected in the jugular vein 1 h before sacrifice.
Positive_regulation (accumulation) of Aortic albumin in jugular vein
18) Confidence 0.61 Published 1985 Journal Diabetologia Section Abstract Doc Link 4018454 Disease Relevance 0.66 Pain Relevance 0.09
There is a small but significant increase in binding with increasing serum albumin concentration both in plasma (rs = 0.549, P = 0.014) and in pure serum albumin solutions (rs = 0.848, P < 0.001).
Positive_regulation (increasing) of albumin in plasma
19) Confidence 0.59 Published 1994 Journal Ann. Clin. Biochem. Section Abstract Doc Link 7832576 Disease Relevance 0.28 Pain Relevance 0.33
In patients in whom urological treatment controlled the disease nutritional support maintained the weight, and stabilized serum albumin and lymphocyte counts.
Positive_regulation (stabilized) of albumin in lymphocyte associated with disease
20) Confidence 0.59 Published 1984 Journal J. Urol. Section Abstract Doc Link 6422056 Disease Relevance 1.08 Pain Relevance 0.14

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