INT39781

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Context Info
Confidence 0.60
First Reported 1985
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 9
Disease Relevance 2.47
Pain Relevance 1.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
muscle 1
Sd (Mus musculus)
Pain Link Frequency Relevance Heat
Physical dependence 2 99.96 Very High Very High Very High
Morphine 6 99.04 Very High Very High Very High
tolerance 3 94.48 High High
addiction 4 93.28 High High
narcan 4 92.72 High High
withdrawal 3 92.36 High High
Central nervous system 1 75.00 Quite High
backache 114 72.40 Quite High
cytokine 18 69.76 Quite High
Pain 55 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Drug Dependence 4 99.96 Very High Very High Very High
Anxiety Disorder 123 94.16 High High
Hypertension 50 90.32 High High
Cancer 53 87.52 High High
Pneumonia 2 76.24 Quite High
Gastroenteritis 2 75.20 Quite High
Morphine Dependence 1 75.00 Quite High
Low Back Pain 120 72.40 Quite High
Cleidocranial Dysplasia 1 57.36 Quite High
Skin Cancer 26 55.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The possible role of succinic dehydrogenase (SD) in producing physical dependence to morphine by affecting tissue respiration was investigated in Swiss albino mice during the development of morphine tolerance through a period of addiction and naloxone withdrawal therapy.
Gene_expression (producing) of SD associated with addiction, physical dependence, narcan, tolerance, withdrawal and morphine
1) Confidence 0.60 Published 1985 Journal Clin Physiol Biochem Section Abstract Doc Link 4040449 Disease Relevance 0.26 Pain Relevance 0.87
The sample of this secondary analysis was significant younger than that of the excluded patients (M: 48 years, SD: 12.9 versus M: 52 years, SD: 14.8; t=4.40, df=780.2, p<.01).
Gene_expression (t=4.40) of SD
2) Confidence 0.14 Published 2009 Journal GMS Psycho-Social-Medicine Section Body Doc Link PMC2736477 Disease Relevance 0.23 Pain Relevance 0.13
The sample of this secondary analysis was significant younger than that of the excluded patients (M: 48 years, SD: 12.9 versus M: 52 years, SD: 14.8; t=4.40, df=780.2, p<.01).
Gene_expression (years) of SD
3) Confidence 0.14 Published 2009 Journal GMS Psycho-Social-Medicine Section Body Doc Link PMC2736477 Disease Relevance 0.22 Pain Relevance 0.13
The sample of this secondary analysis was significant younger than that of the excluded patients (M: 48 years, SD: 12.9 versus M: 52 years, SD: 14.8; t=4.40, df=780.2, p<.01).
Gene_expression (14.8) of SD
4) Confidence 0.14 Published 2009 Journal GMS Psycho-Social-Medicine Section Body Doc Link PMC2736477 Disease Relevance 0.23 Pain Relevance 0.13
Characteristics of SD rat model
Gene_expression (model) of SD
5) Confidence 0.08 Published 2007 Journal BMC Cancer Section Body Doc Link PMC1821034 Disease Relevance 0.67 Pain Relevance 0.03
These analyses revealed no significant differences in age between participants (M = 57.15, SD = 7.13) and non-participants (M = 57.02, SD = 7.38; t(6,418) = 0.62, p > .05), nor for gender, (?
Gene_expression (7.38) of SD
6) Confidence 0.05 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2443140 Disease Relevance 0.42 Pain Relevance 0
These analyses revealed no significant differences in age between participants (M = 57.15, SD = 7.13) and non-participants (M = 57.02, SD = 7.38; t(6,418) = 0.62, p > .05), nor for gender, (?
Gene_expression (57.15) of SD
7) Confidence 0.05 Published 2008 Journal BMC Public Health Section Body Doc Link PMC2443140 Disease Relevance 0.41 Pain Relevance 0
The following calculations were performed: (1) basic calculation of PV, following the IPL method; (2) mean CV, expressed as an average value of the PVs; (3) within-subject skewness of the peak velocities (Sk-PV), expressed as a skewness of a PVs’ population of a subject; (4) within-subject standard deviation of the peak velocities (SD-PV), expressed as a standard deviation of a PVs’ population of a subject; and (5) peak frequency (PF), expressed as a number of peaks per second.


Gene_expression (expressed) of SD-PV
8) Confidence 0.05 Published 2007 Journal Eur J Appl Physiol Section Body Doc Link PMC2039775 Disease Relevance 0 Pain Relevance 0
In the present study, the sEMG signal was described with four parameters derived from the IPL method: (1) the mean muscle CV which was the average of the obtained MUP velocities; the two statistical distribution variables, which were: (2) the within-subject MUP velocities’ skewness [Sk-peak velocity (PV)] and (3) the within-subject MUP velocities’ standard deviation (SD-PV), and (4) the peak frequency (PF), a variable expressing the amount of MUP activity (number of peaks = MUPs) per second.
Gene_expression (expressing) of SD-PV in muscle
9) Confidence 0.04 Published 2007 Journal Eur J Appl Physiol Section Body Doc Link PMC2039775 Disease Relevance 0.05 Pain Relevance 0.04

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