INT39818

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Context Info
Confidence 0.45
First Reported 1985
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 8
Total Number 8
Disease Relevance 3.36
Pain Relevance 1.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Cfd) extracellular space (Cfd) extracellular region (Cfd)
Anatomy Link Frequency
bar 1
ADN 1
vagus nerve 1
Cfd (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Action potential 12 100.00 Very High Very High Very High
vagus nerve 1 99.40 Very High Very High Very High
ketamine 1 98.12 Very High Very High Very High
Clonidine 5 97.96 Very High Very High Very High
anesthesia 11 97.24 Very High Very High Very High
isoflurane 10 83.32 Quite High
depression 8 65.44 Quite High
qutenza 80 50.00 Quite Low
imagery 59 50.00 Quite Low
amygdala 15 42.64 Quite Low
Disease Link Frequency Relevance Heat
Aggression 93 100.00 Very High Very High Very High
Burns 22 99.84 Very High Very High Very High
Muscle Hypertonia 28 97.56 Very High Very High Very High
Rheumatoid Arthritis 2 92.40 High High
Hypoxia 8 91.36 High High
Injury 4 75.00 Quite High
Hypertension 3 75.00 Quite High
Shock 4 20.80 Low Low
Nociception 2 11.40 Low Low
Urological Neuroanatomy 14 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Note the robust activation of this "aggression area" in Fig 3, sections D-F, in response to mate/intruder but not to any other stimulus conditions.
Positive_regulation (activation) of D-F associated with aggression
1) Confidence 0.45 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2601047 Disease Relevance 0.28 Pain Relevance 0
The attenuated depressor and sympatho-inhibitory responses to ADN stimulation in SHR were restored following i.v. injections of clonidine, although the drug did not affect the responses to ADN stimulations in WKY.
Positive_regulation (stimulation) of ADN in ADN associated with clonidine
2) Confidence 0.44 Published 1993 Journal Jpn Heart J Section Abstract Doc Link 8411638 Disease Relevance 0.07 Pain Relevance 0.43
HR responses to electrical stimulation of the left ADN and the right vagus nerve were assessed under ketamine-acepromazine anesthesia.
Positive_regulation (stimulation) of ADN in vagus nerve associated with anesthesia, ketamine and vagus nerve
3) Confidence 0.28 Published 2007 Journal Am. J. Physiol. Heart Circ. Physiol. Section Abstract Doc Link 17693540 Disease Relevance 0.70 Pain Relevance 0.24
As shown in the bar graphs of Figure 8C and in contrast to lesions of SubLC and PO, lesions of the DLPT produced a sizable increase in the mean bout duration of atonia (t = 6.7, df = 11, p < 0.01) and a decrease in the mean bout duration of high muscle tone (t = 3.3, df = 11, p < 0.01).
Positive_regulation (increase) of df in bar associated with muscle hypertonia
4) Confidence 0.23 Published 2005 Journal PLoS Biology Section Body Doc Link PMC1079781 Disease Relevance 0.24 Pain Relevance 0
Consequently, as indicated by the pie charts in Figure 8C, the percentage of time in atonia was significantly increased in the lesion group (t = 6.4, df = 11, p < 0.0001).
Positive_regulation (increased) of df
5) Confidence 0.23 Published 2005 Journal PLoS Biology Section Body Doc Link PMC1079781 Disease Relevance 0.28 Pain Relevance 0
Compound action potentials in ADN
Positive_regulation (potentials) of ADN associated with action potential
6) Confidence 0.22 Published 2006 Journal J Negat Results Biomed Section Body Doc Link PMC1481593 Disease Relevance 0 Pain Relevance 0.12
T4DF (both days) and T3DF (day 14) were significantly elevated in BURN, demonstrating a deficit in serum binding, but T3U was not.
Positive_regulation (elevated) of T3DF associated with burns
7) Confidence 0.04 Published 1985 Journal J Trauma Section Abstract Doc Link 4046084 Disease Relevance 0.89 Pain Relevance 0.18
T4DF (both days) and T3DF (day 14) were significantly elevated in BURN, demonstrating a deficit in serum binding, but T3U was not.
Positive_regulation (elevated) of T4DF associated with burns
8) Confidence 0.04 Published 1985 Journal J Trauma Section Abstract Doc Link 4046084 Disease Relevance 0.89 Pain Relevance 0.18

General Comments

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