INT39819

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Context Info
Confidence 0.62
First Reported 1985
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.10
Pain Relevance 0.72

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (C4A) extracellular region (C4A)
Anatomy Link Frequency
spine 1
anterior 1
PC-3 1
C4A (Homo sapiens)
Pain Link Frequency Relevance Heat
Dermatone 2 97.80 Very High Very High Very High
hyperpathia 2 96.84 Very High Very High Very High
anesthesia 2 95.84 Very High Very High Very High
bradykinin 3 85.00 Quite High
Spinal cord 7 82.64 Quite High
metalloproteinase 18 67.68 Quite High
cytokine 5 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Neurotransmitter 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Dislocations 6 100.00 Very High Very High Very High
Quadriplegia 6 99.40 Very High Very High Very High
Hyperalgesia 2 96.84 Very High Very High Very High
Injury 8 91.84 High High
Infection 19 90.12 High High
Hereditary Angioedema 41 87.84 High High
Frailty 6 82.64 Quite High
Malignant Neoplastic Disease 6 80.32 Quite High
Prostate Cancer 87 78.48 Quite High
Intervertebral Disk Displacement 2 78.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
[A case of traumatic anterior dislocation of C4 recovered from complete tetraplegia].
Localization (recovered) of C4 in anterior associated with quadriplegia and dislocations
1) Confidence 0.62 Published 1985 Journal No Shinkei Geka Section Title Doc Link 4047327 Disease Relevance 1.10 Pain Relevance 0.27
Plain films of the cervical spine disclosed anterior dislocation of C4 upon C5 approximately 6 mm and possible disc herniation of C4/5.
Localization (dislocation) of C4 in spine associated with dislocations
2) Confidence 0.62 Published 1985 Journal No Shinkei Geka Section Abstract Doc Link 4047327 Disease Relevance 1.05 Pain Relevance 0.31
PC-3 and C4-2 secrete more u-PA than LNCaP cells [116,117], which is most notably involved in the regulation of ECM-laminin degradation, thereby allowing for PC-3 and C4-2 cells to behave more aggressively.
Localization (secrete) of C4-2 in PC-3
3) Confidence 0.05 Published 2004 Journal Reprod Biol Endocrinol Section Body Doc Link PMC320496 Disease Relevance 0.23 Pain Relevance 0.03
The C1-INH molecule is also supposed to regulate the MBL pathway via inhibition of MBL-associated serine proteases (MASPs), of which MASP-2 cleaves C4 much more efficiently than C1s does [22].
Localization (cleaves) of C4
4) Confidence 0.04 Published 2008 Journal Arch Immunol Ther Exp (Warsz) Section Body Doc Link PMC2734250 Disease Relevance 0.72 Pain Relevance 0.10

General Comments

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