INT39834

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Context Info
Confidence 0.49
First Reported 1985
Last Reported 2011
Negated 1
Speculated 1
Reported most in Body
Documents 6
Total Number 7
Disease Relevance 3.14
Pain Relevance 1.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cp) oxidoreductase activity (Cp) aging (Cp)
extracellular region (Cp)
Anatomy Link Frequency
semen 2
astrocytes 2
Cp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 71 99.96 Very High Very High Very High
Angina 1 96.16 Very High Very High Very High
tolerance 2 93.80 High High
cytokine 14 93.36 High High
Prostatitis 33 92.84 High High
cINOD 1 90.32 High High
Nerve growth factor 5 84.56 Quite High
Glutamate 23 53.36 Quite High
Eae 3 50.00 Quite Low
Neuropathic pain 2 50.00 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 79 99.96 Very High Very High Very High
Coronary Artery Disease 2 99.84 Very High Very High Very High
Injury 93 99.36 Very High Very High Very High
Varicocele 1 98.72 Very High Very High Very High
Diabetes Mellitus 63 97.76 Very High Very High Very High
Cv General 3 Under Development 2 96.16 Very High Very High Very High
Reprotox - General 3 2 95.92 Very High Very High Very High
Nervous System Injury 2 94.28 High High
Prostatitis 33 92.84 High High
Pressure And Volume Under Development 1 90.24 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Reduced GSH levels and the ceruloplasmin/transferrin ratio were determined as measures of overall antioxidant activity.
Positive_regulation (Reduced) of Gene_expression (ratio) of ceruloplasmin
1) Confidence 0.49 Published 2009 Journal J. Surg. Res. Section Body Doc Link 18708193 Disease Relevance 0.09 Pain Relevance 0
In another study we demonstrated that the expression of ceruloplasmin (CP) is induced by a traumatic injury and that IL-1 is responsible for the injury-induced expression of CP in astrocytes [34].
Positive_regulation (induced) of Gene_expression (expression) of ceruloplasmin in astrocytes associated with injury
2) Confidence 0.45 Published 2006 Journal J Neuroinflammation Section Body Doc Link PMC1533808 Disease Relevance 0.99 Pain Relevance 0.22
[The clinico-hemodynamic effects of the antioxidant ceruloplasmin in IHD patients].
Positive_regulation (effects) of Gene_expression (effects) of ceruloplasmin associated with coronary artery disease
3) Confidence 0.43 Published 1995 Journal Ter. Arkh. Section Title Doc Link 7784970 Disease Relevance 0.28 Pain Relevance 0.19
Insulin treatment partially normalized the protein expression of Cp, Lgals3, and Stat3 with the insulin-treated group no longer significantly elevated from control but also not significantly lower than the diabetic group (Figure 7).
Neg (no) Positive_regulation (elevated) of Gene_expression (expression) of Cp associated with diabetes mellitus
4) Confidence 0.19 Published 2011 Journal PLoS ONE Section Body Doc Link PMC3020973 Disease Relevance 0.33 Pain Relevance 0
Role of ceruloplasmin in inflammation: increased serum ceruloplasmin levels during inflammatory conditions and its possible relationship with anti-inflammatory agents.
Spec (possible) Positive_regulation (increased) of Gene_expression (levels) of serum ceruloplasmin associated with inflammation
5) Confidence 0.18 Published 1985 Journal Pharmacol Res Commun Section Title Doc Link 4048245 Disease Relevance 0.64 Pain Relevance 0.53
TAC levels and ROS-TAC scores in semen of patients with CP were much lower than in the control group, suggesting that antioxidant supplements might be helpful for patients with CP.28 ROS level was the highest in patients with CP as well as varicocele and ROS-TAC score was suggested as a possible predictor of infertility.29
Positive_regulation (highest) of Gene_expression (level) of CP in semen associated with reprotox - general 3 and varicocele
6) Confidence 0.13 Published 2009 Journal Yonsei Medical Journal Section Body Doc Link PMC2703763 Disease Relevance 0.81 Pain Relevance 0.24
Cp value of the control group to yield the ??
Positive_regulation (value) of Gene_expression (value) of Cp
7) Confidence 0.07 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC3001741 Disease Relevance 0 Pain Relevance 0

General Comments

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