INT39835

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Context Info
Confidence 0.75
First Reported 1985
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 7
Disease Relevance 8.81
Pain Relevance 0.77

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Cpn1) extracellular space (Cpn1) extracellular region (Cpn1)
Anatomy Link Frequency
vein 3
saphenous veins 1
Cpn1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 76 97.56 Very High Very High Very High
cINOD 1 95.52 Very High Very High Very High
ischemia 6 51.40 Quite High
Percutaneous transluminal coronary angioplasty 6 16.72 Low Low
Angina 12 10.12 Low Low
cytokine 6 5.00 Very Low Very Low Very Low
anesthesia 6 5.00 Very Low Very Low Very Low
imagery 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pneumonia 306 100.00 Very High Very High Very High
Infection 60 100.00 Very High Very High Very High
INFLAMMATION 75 97.56 Very High Very High Very High
Edema 18 92.32 High High
Atherosclerosis 30 92.08 High High
Hypertrophy 18 91.48 High High
Increased Venous Pressure Under Development 12 90.28 High High
Hyperplasia 102 86.20 High High
Chlamydia Infection 42 84.52 Quite High
Acute Coronary Syndrome 6 79.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Bartels et al.[21] studied the prevalence of Cpn in occluded vein grafts and native saphenous veins and showed that Cpn was frequently present in occluded CABG but not in normal veins.
Neg (not) Gene_expression (present) of Cpn in saphenous veins associated with pneumonia
1) Confidence 0.75 Published 2007 Journal BMC Microbiol Section Body Doc Link PMC2222630 Disease Relevance 1.45 Pain Relevance 0.03
m in grafted vein of the control group) and showed neointimal thickening, which is principally absent in non-grafted control veins.Cpn administration immediately after vein grafting resulted in a significant increase in the medial thickness (Cpn-group: 50 ± 3 ?
Gene_expression (group) of Cpn in vein associated with pneumonia
2) Confidence 0.65 Published 2007 Journal BMC Microbiol Section Body Doc Link PMC2222630 Disease Relevance 0.97 Pain Relevance 0
m2 was not significantly different between groups (Cpn-group: 5.0 ± 0.7 × 10-3 cells/?
Gene_expression (group) of Cpn associated with pneumonia
3) Confidence 0.65 Published 2007 Journal BMC Microbiol Section Body Doc Link PMC2222630 Disease Relevance 1.18 Pain Relevance 0.07
In addition, recent studies have shown that Cpn infection promotes a proliferative phenotype in the vasculature, which makes Cpn also a likely risk factor for vein graft failure [9,10].
Gene_expression (infection) of Cpn in vein associated with pneumonia and infection
4) Confidence 0.65 Published 2007 Journal BMC Microbiol Section Body Doc Link PMC2222630 Disease Relevance 1.95 Pain Relevance 0.17
m in grafted vein of the control group) and showed neointimal thickening, which is principally absent in non-grafted control veins.Cpn administration immediately after vein grafting resulted in a significant increase in the medial thickness (Cpn-group: 50 ± 3 ?
Gene_expression (administration) of Cpn in vein associated with pneumonia
5) Confidence 0.65 Published 2007 Journal BMC Microbiol Section Body Doc Link PMC2222630 Disease Relevance 1.07 Pain Relevance 0
Significant increase of serum CPN levels was observed in all experimental animal models with induced inflammatory conditions.
Gene_expression (levels) of CPN associated with inflammation
6) Confidence 0.60 Published 1985 Journal Pharmacol Res Commun Section Abstract Doc Link 4048245 Disease Relevance 0.59 Pain Relevance 0.41
These studies suggest that Cpn is present in occluded grafts, however, experimental evidence for this is currently lacking.
Gene_expression (present) of Cpn associated with pneumonia
7) Confidence 0.58 Published 2007 Journal BMC Microbiol Section Body Doc Link PMC2222630 Disease Relevance 1.59 Pain Relevance 0.09

General Comments

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