INT39837

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.69
First Reported 1985
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 6
Total Number 8
Disease Relevance 6.20
Pain Relevance 2.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Cpn1) extracellular space (Cpn1) extracellular region (Cpn1)
Anatomy Link Frequency
vein 3
spines 1
caudate-putamen 1
body 1
Cpn1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Delta opioid receptors 9 100.00 Very High Very High Very High
Inflammation 63 99.12 Very High Very High Very High
cINOD 3 96.24 Very High Very High Very High
Opioid 2 96.16 Very High Very High Very High
opioid receptor 4 95.20 Very High Very High Very High
mu opioid receptor 4 75.00 Quite High
Endogenous opioid 1 50.96 Quite High
ischemia 3 42.08 Quite Low
Neurotransmitter 1 25.00 Low Low
Percutaneous transluminal coronary angioplasty 3 7.40 Low Low
Disease Link Frequency Relevance Heat
Pneumonia 153 100.00 Very High Very High Very High
INFLAMMATION 60 99.12 Very High Very High Very High
Infection 30 91.20 High High
Atherosclerosis 15 86.64 High High
Increased Venous Pressure Under Development 6 84.84 Quite High
Hyperplasia 51 83.12 Quite High
Chlamydia Infection 21 81.44 Quite High
Thrombosis 9 75.80 Quite High
Acute Coronary Syndrome 3 73.80 Quite High
Body Weight 6 67.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Significant increase of serum CPN levels was observed in all experimental animal models with induced inflammatory conditions.
Positive_regulation (increase) of CPN associated with inflammation
1) Confidence 0.69 Published 1985 Journal Pharmacol Res Commun Section Abstract Doc Link 4048245 Disease Relevance 0.59 Pain Relevance 0.41
m in grafted vein of the control group) and showed neointimal thickening, which is principally absent in non-grafted control veins.Cpn administration immediately after vein grafting resulted in a significant increase in the medial thickness (Cpn-group: 50 ± 3 ?
Positive_regulation (increase) of Cpn in vein associated with pneumonia
2) Confidence 0.67 Published 2007 Journal BMC Microbiol Section Body Doc Link PMC2222630 Disease Relevance 0.98 Pain Relevance 0
The concurrent increase of serum CPN level during induced inflammatory conditions suggest the involvement of serum CPN as one of the body's inbuilt defensive mechanism against noxious responses or inflammation.
Positive_regulation (increase) of CPN in body associated with inflammation
3) Confidence 0.46 Published 1985 Journal Pharmacol Res Commun Section Abstract Doc Link 4048245 Disease Relevance 0.68 Pain Relevance 0.42
It is suggested that the increased serum CPN levels may be a complimentary factor associated with inflammatory conditions.
Positive_regulation (increased) of CPN associated with inflammation
4) Confidence 0.46 Published 1985 Journal Pharmacol Res Commun Section Abstract Doc Link 4048245 Disease Relevance 0.66 Pain Relevance 0.42
This is supported by the work of Bartels et al., who observed a strong correlation between elevated Cpn IgG titers and the detection of Cpn in occluded vein grafts [11].
Positive_regulation (elevated) of Cpn in vein associated with pneumonia
5) Confidence 0.45 Published 2007 Journal BMC Microbiol Section Body Doc Link PMC2222630 Disease Relevance 1.84 Pain Relevance 0.13
Cpn DNA could be detected by PCR in 25% of the cases, while viable Cpn was recovered from 16% of occluded vein grafts.
Positive_regulation (recovered) of Cpn in vein associated with pneumonia
6) Confidence 0.39 Published 2007 Journal BMC Microbiol Section Body Doc Link PMC2222630 Disease Relevance 1.45 Pain Relevance 0.03
From P15, a few immunogold particles were seen in contact with postsynaptic densities in spines, and the proportion of these particles significantly increased in P30 and adult CPN.
Positive_regulation (increased) of CPN in spines
7) Confidence 0.24 Published 2003 Journal J. Comp. Neurol. Section Abstract Doc Link 14608598 Disease Relevance 0 Pain Relevance 0.28
The activation of delta-opioid receptors (DORs) in the caudate-putamen nucleus (CPN) produces regionally distinct changes in motor functions, many of which are also influenced by opioids active at micro-opioid receptors (MORs).
Positive_regulation (activation) of CPN in caudate-putamen associated with opioid receptor, delta opioid receptors and opioid
8) Confidence 0.23 Published 2001 Journal J. Neurosci. Section Abstract Doc Link 11312309 Disease Relevance 0 Pain Relevance 0.37

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox