INT39838

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Context Info
Confidence 0.17
First Reported 1985
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 7
Disease Relevance 0.64
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cp) oxidoreductase activity (Cp) aging (Cp)
extracellular region (Cp)
Anatomy Link Frequency
brain 2
Cp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 50 100.00 Very High Very High Very High
Substantia nigra 3 100.00 Very High Very High Very High
Enkephalin 2 100.00 Very High Very High Very High
cINOD 1 90.32 High High
Opioid 1 59.08 Quite High
alcohol 1 56.28 Quite High
Endogenous opioid 1 52.48 Quite High
Spinal cord 97 5.00 Very Low Very Low Very Low
Inflammatory response 66 5.00 Very Low Very Low Very Low
bDMF 18 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 115 100.00 Very High Very High Very High
Apoptosis 189 41.76 Quite Low
Injury 196 33.96 Quite Low
Spinal Cord Injury 184 27.12 Quite Low
Death 81 5.00 Very Low Very Low Very Low
Contusions 51 5.00 Very Low Very Low Very Low
Spinal Injuries 34 5.00 Very Low Very Low Very Low
Stress 25 5.00 Very Low Very Low Very Low
Nervous System Malformation 20 5.00 Very Low Very Low Very Low
Ganglion Cysts 20 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Alterations in enkephalin expression in the substantia nigra and CP in response to ethanol exposure could be involved in the mechanisms underlying brain sensitivity to the drug.
Regulation (Alterations) of Gene_expression (expression) of CP in brain associated with substantia nigra and enkephalin
1) Confidence 0.17 Published 2008 Journal J. Mol. Neurosci. Section Abstract Doc Link 18227978 Disease Relevance 0 Pain Relevance 0.38
Role of ceruloplasmin in inflammation: increased serum ceruloplasmin levels during inflammatory conditions and its possible relationship with anti-inflammatory agents.
Regulation (Role) of Gene_expression (levels) of serum ceruloplasmin associated with inflammation
2) Confidence 0.16 Published 1985 Journal Pharmacol Res Commun Section Title Doc Link 4048245 Disease Relevance 0.64 Pain Relevance 0.53
In the cases where we custom designed PCR primers, the average Cp values were compared to the Cp value of the reference gene glyceraldehyde 3-phosphate dehydrogenase (Gadph), to give us the ?
Regulation (compared) of Gene_expression (value) of Cp
3) Confidence 0.07 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC3001741 Disease Relevance 0 Pain Relevance 0
In the cases where we custom designed PCR primers, the average Cp values were compared to the Cp value of the reference gene glyceraldehyde 3-phosphate dehydrogenase (Gadph), to give us the ?
Regulation (compared) of Gene_expression (value) of Cp
4) Confidence 0.07 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC3001741 Disease Relevance 0 Pain Relevance 0
The average Cp value for each gene of interest (GOI), both in non-injured controls and spinally transected animals, was calculated and then compared to a given set of reference genes included on the plate to give us the ?
Regulation (calculated) of Gene_expression (value) of Cp
5) Confidence 0.03 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2894843 Disease Relevance 0 Pain Relevance 0
The average Cp value for each gene of interest (GOI), both in non-injured controls and spinally transected animals, was calculated and then compared to a given set of reference genes included on the plate to give us the ?
Regulation (controls) of Gene_expression (value) of Cp
6) Confidence 0.03 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2894843 Disease Relevance 0 Pain Relevance 0
The average Cp value for each gene of interest (GOI), both in non-injured controls and spinally transected animals, was calculated and then compared to a given set of reference genes included on the plate to give us the ?
Regulation (average) of Gene_expression (value) of Cp
7) Confidence 0.03 Published 2010 Journal BMC Neurosci Section Body Doc Link PMC2894843 Disease Relevance 0 Pain Relevance 0

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