INT39865

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Context Info
Confidence 0.27
First Reported 1985
Last Reported 2009
Negated 1
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 0.71
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein modification process (PLOD1) endoplasmic reticulum (PLOD1)
Anatomy Link Frequency
plasma 2
nodules 2
PLOD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Dopamine 4 99.74 Very High Very High Very High
narcan 3 97.60 Very High Very High Very High
Enkephalin 1 90.76 High High
Opioid 2 82.08 Quite High
agonist 5 81.12 Quite High
endometriosis 6 79.08 Quite High
Pain 2 62.00 Quite High
antagonist 4 26.96 Quite Low
pain pelvic 3 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 9 85.36 High High
Endometrial Cancer 1 81.20 Quite High
Carcinoma 4 80.28 Quite High
Endometriosis (extended) 29 79.08 Quite High
Disease 3 78.12 Quite High
Uterine Fibroids 3 69.68 Quite High
Uterine Hemorrhage 1 63.68 Quite High
Pain 2 62.00 Quite High
Incontinence 1 57.68 Quite High
Hemorrhage 1 51.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In these patients, sulpiride pretreatment counteracted the inhibitory effect of dopamine but did not alter the fall of LH plasma levels that DAMME induced.
Neg (not) Regulation (alter) of Positive_regulation (induced) of LH plasma in plasma associated with dopamine
1) Confidence 0.27 Published 1985 Journal Fertil. Steril. Section Abstract Doc Link 4054321 Disease Relevance 0 Pain Relevance 0.52
The identification of luteinizing hormone (LH) receptors in LPD nodules from a postmenopausal woman suggests that the typical postmenopausal increase in LH levels might affect the pathogenesis of this condition [22].
Spec (might) Regulation (affect) of Positive_regulation (increase) of LH in nodules
2) Confidence 0.16 Published 2006 Journal BMC Cancer Section Body Doc Link PMC1481579 Disease Relevance 0.71 Pain Relevance 0.10
Although some studies have failed to show an effect of LH supplementation in older women (?
Regulation (effect) of Positive_regulation (supplementation) of LH
3) Confidence 0.13 Published 2009 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2764709 Disease Relevance 0 Pain Relevance 0.04

General Comments

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