INT39906

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Context Info
Confidence 0.21
First Reported 1985
Last Reported 2004
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 1.34
Pain Relevance 2.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (ALKBH2) oxidoreductase activity (ALKBH2) nucleus (ALKBH2)
Anatomy Link Frequency
blood 2
ALKBH2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Oxycodone 46 100.00 Very High Very High Very High
drug abuse 18 90.24 High High
Opioid 6 45.72 Quite Low
alcohol 2 43.88 Quite Low
Dismenorea 1 41.84 Quite Low
tolerance 2 25.00 Low Low
Disease Link Frequency Relevance Heat
Drug Dependence 18 90.24 High High
Toxicity 6 53.92 Quite High
Reprotox - General 1 1 41.84 Quite Low
Death 8 41.00 Quite Low
Pre-term Labor 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Assessment of blood levels determined by specific assay methodology (primarily gas chromatography-mass spectrometry) in these cases provided the following mean postmortem concentrations of OXC: multiple drug-induced deaths, OxyContin identified, 0.93 mg/mL (N = 167); multiple drug-induced deaths, OxyContin not identified, 0.73 mg/mL (N = 579); single (OXC) drug-induced deaths, OxyContin identified, 1.55 mg/mL (N = 12); and single (OXC) drug-induced deaths, OxyContin not identified, 1.70 mg/mL (N = 15).
Gene_expression (identified) of OxyContin in blood associated with oxycodone
1) Confidence 0.21 Published 2004 Journal J Anal Toxicol Section Abstract Doc Link 15189671 Disease Relevance 0.63 Pain Relevance 1.46
Assessment of blood levels determined by specific assay methodology (primarily gas chromatography-mass spectrometry) in these cases provided the following mean postmortem concentrations of OXC: multiple drug-induced deaths, OxyContin identified, 0.93 mg/mL (N = 167); multiple drug-induced deaths, OxyContin not identified, 0.73 mg/mL (N = 579); single (OXC) drug-induced deaths, OxyContin identified, 1.55 mg/mL (N = 12); and single (OXC) drug-induced deaths, OxyContin not identified, 1.70 mg/mL (N = 15).
Gene_expression (identified) of OxyContin in blood associated with oxycodone
2) Confidence 0.21 Published 2004 Journal J Anal Toxicol Section Abstract Doc Link 15189671 Disease Relevance 0.71 Pain Relevance 1.48
The effect was compared with that of a previously synthesized analogue 1-deamino-Tyr(OEt)-oxytocin (dE-OXY) which has already been tested in nonpregnant and pregnant women in vivo.
Gene_expression (synthesized) of dE-OXY
3) Confidence 0.15 Published 1985 Journal Acta Obstet Gynecol Scand Section Abstract Doc Link 4061066 Disease Relevance 0 Pain Relevance 0

General Comments

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