INT39911

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Context Info
Confidence 0.41
First Reported 1985
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 2.57
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Pth) extracellular region (Pth) cellular_component (Pth)
Anatomy Link Frequency
parathyroid 6
plasma 2
Pth (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 5 95.48 Very High Very High Very High
Analgesic 4 75.00 Quite High
Disease Link Frequency Relevance Heat
Hypocalcemia 2 99.90 Very High Very High Very High
Renal Disease 10 97.76 Very High Very High Very High
Pain 2 95.48 Very High Very High Very High
Renal Osteodystrophy 1 94.88 High High
Body Weight 2 93.24 High High
Osteogenesis Imperfecta 25 91.88 High High
Fatigue 1 85.92 High High
Fever 3 85.04 High High
Hypercalcemia 10 84.68 Quite High
Myalgia 1 83.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, their values, were decreased gradually with the elevation of parathyroid hormone level.
Negative_regulation (decreased) of Positive_regulation (elevation) of parathyroid hormone in parathyroid
1) Confidence 0.41 Published 1994 Journal Hinyokika Kiyo Section Abstract Doc Link 8191970 Disease Relevance 0.43 Pain Relevance 0.14
Treatment with a new calcimimetic agent, cinacalcet HCl (Mimpara, Amgen, Munich, Germany), resulted in a rapid decline in elevated parathyroid hormone levels, near normalization of other laboratory markers of bone metabolism, improvement in mobility and skeletal pain caused by renal osteodystrophy, and an increase in body weight.
Negative_regulation (decline) of Positive_regulation (elevated) of parathyroid hormone in parathyroid associated with pain, renal osteodystrophy and body weight
2) Confidence 0.41 Published 2008 Journal J Ren Nutr Section Abstract Doc Link 18558304 Disease Relevance 0.61 Pain Relevance 0.10
Treatment reduced inappropriately elevated parathyroid hormone levels, presumably caused by long-term bisphosphonate use.
Negative_regulation (reduced) of Positive_regulation (elevated) of parathyroid hormone in parathyroid
3) Confidence 0.41 Published 2010 Journal Cancer Section Body Doc Link 19918922 Disease Relevance 0.12 Pain Relevance 0
The degree of hypocalcemia was related to the increase in plasma PTH and alkaline phosphatase, but not to the plasma level of 25(OH)D or 1,25(OH)2D.
Neg (not) Negative_regulation (related) of Neg (not) Positive_regulation (increase) of PTH in plasma associated with hypocalcemia
4) Confidence 0.24 Published 1985 Journal Am. J. Nephrol. Section Abstract Doc Link 4061503 Disease Relevance 0.61 Pain Relevance 0.13
Serum calcium levels transiently decreased with a transitory increase in PTH levels during pamidronate therapy (10, 11).
Negative_regulation (decreased) of Positive_regulation (increase) of PTH
5) Confidence 0.14 Published 2007 Journal Journal of Korean Medical Science Section Body Doc Link PMC2693583 Disease Relevance 0.80 Pain Relevance 0

General Comments

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