INT39999

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.59
First Reported 1981
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 7
Total Number 8
Disease Relevance 3.27
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

hydrolase activity, acting on glycosyl bonds (Gla) extracellular region (Gla) Golgi apparatus (Gla)
lysosome (Gla) cytoplasm (Gla)
Anatomy Link Frequency
AGS 2
Gla (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 115 89.44 High High
Substantia nigra 8 84.32 Quite High
Ventral tegmentum 8 82.64 Quite High
Serotonin 5 75.00 Quite High
fluoxetine 1 74.88 Quite High
midbrain 15 73.76 Quite High
unmyelinated 2 72.16 Quite High
Pain 3 65.04 Quite High
monoamine 4 58.12 Quite High
Inflammation 11 16.48 Low Low
Disease Link Frequency Relevance Heat
Alagille Syndrome 30 100.00 Very High Very High Very High
Stress 16 99.20 Very High Very High Very High
Targeted Disruption 12 94.68 High High
Disease 12 87.20 High High
Stomach Cancer 22 84.40 Quite High
Syndrome 2 83.28 Quite High
Anxiety Disorder 3 83.16 Quite High
Epilepsy 2 75.00 Quite High
Hypertrophy 3 64.64 Quite High
Brain Tumor 1 57.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Results indicate that although reduced stress reactivity promotes exploration, this does not translate into an up-regulation of GLA, suggesting that the relationship between GLA and exploration is not mediated by stress reactivity.
Gene_expression (exploration) of GLA associated with stress
1) Confidence 0.59 Published 2007 Journal Behav. Neurosci. Section Abstract Doc Link 17907827 Disease Relevance 0.65 Pain Relevance 0
Moreover, the thermolabile isoenzyme A of alpha-D-galactosidase was almost completely absent.
Neg (absent) Gene_expression (absent) of alpha-D-galactosidase
2) Confidence 0.58 Published 1981 Journal Muscle Nerve Section Abstract Doc Link 6793867 Disease Relevance 0.24 Pain Relevance 0.13
However, CDP-treated mice did not exhibit facilitated acquisition of any of the learning tasks and expressed GLA comparable to controls.
Gene_expression (expressed) of GLA
3) Confidence 0.53 Published 2007 Journal Behav. Neurosci. Section Abstract Doc Link 17907827 Disease Relevance 0.67 Pain Relevance 0
These results suggest, first of all, that the inhibition of AGS produced by 6-MeO-THBC is a consequence of its combined MAO-A and 5-HT uptake inhibition properties.
Gene_expression (produced) of AGS in AGS associated with alagille syndrome
4) Confidence 0.48 Published 1985 Journal Pharmacol. Biochem. Behav. Section Abstract Doc Link 4080761 Disease Relevance 0.91 Pain Relevance 0.17
Selected phage GLA.
Gene_expression (Selected) of GLA
5) Confidence 0.26 Published 2010 Journal Pharm Res Section Body Doc Link PMC2837178 Disease Relevance 0 Pain Relevance 0
Fig. 4Incubation of selected phage GLA, GYR, GTW and control phage YLR with hCMEC/D3 and HUVEC cells, recovery expressed as a percentage of the input.
Gene_expression (selected) of GLA
6) Confidence 0.26 Published 2010 Journal Pharm Res Section Body Doc Link PMC2837178 Disease Relevance 0 Pain Relevance 0
BSR-transfected AGS–GFP cells (Figure 6B), thus suggesting the existence of an NF-?
Gene_expression (transfected) of AGS in AGS associated with alagille syndrome
7) Confidence 0.05 Published 2008 Journal EMBO J Section Body Doc Link PMC2413189 Disease Relevance 0.48 Pain Relevance 0
In a previous report we first detected DAT-Cre mediated beta galactosidase expression in a conditional Rosa26LacZ reporter mice at embryonic day 17 [15], suggesting excision of Pten exon5 at around this developmental point.
Gene_expression (expression) of galactosidase
8) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2736587 Disease Relevance 0.33 Pain Relevance 0.39

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox