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Context Info
Confidence 0.44
First Reported 1984
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.57
Pain Relevance 1.30

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (POMC) cell-cell signaling (POMC) cytoplasm (POMC)
extracellular space (POMC) generation of precursor metabolites and energy (POMC) signal transduction (POMC)
Anatomy Link Frequency
putamen 2
body 2
POMC (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 2 100.00 Very High Very High Very High
noradrenaline 1 100.00 Very High Very High Very High
halothane 10 99.68 Very High Very High Very High
Catecholamine 2 99.60 Very High Very High Very High
Dynorphin 1 99.22 Very High Very High Very High
depression 15 86.88 High High
Glutamate 1 84.80 Quite High
cryotherapy 38 79.84 Quite High
Neuropeptide 1 77.20 Quite High
Opioid 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Schizophrenia 3 99.40 Very High Very High Very High
Heart Rate Under Development 1 86.88 High High
Disease 1 83.28 Quite High
Occupational Lung Diseases 1 76.64 Quite High
Arrhythmia Under Development 1 59.76 Quite High
Depression 26 50.00 Quite Low
Pressure And Volume Under Development 1 43.36 Quite Low
Lichen 1 36.84 Quite Low
Psoriasis 1 36.04 Quite Low
Demyelinating Disease 1 34.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, a significant increase in the formation of the putative neuroleptic-like peptide fragment des-enkephalin-gamma-endorphin in postmortem schizophrenic putamen versus controls was shown.
Positive_regulation (increase) of Phosphorylation (formation) of des-enkephalin-gamma-endorphin in putamen associated with enkephalin and schizophrenia
1) Confidence 0.44 Published 1984 Journal Peptides Section Abstract Doc Link 6085162 Disease Relevance 0.35 Pain Relevance 0.14
The concentrations of met-enkephalin, dynorphin and catecholamines did not change and those of beta-endorphin, adrenocorticotrophin, arginine vasopressin and cortisol increased during halothane anaesthesia.
Positive_regulation (increased) of Phosphorylation (those) of beta-endorphin associated with dynorphin, catecholamine, halothane and enkephalin
2) Confidence 0.43 Published 1995 Journal Res. Vet. Sci. Section Abstract Doc Link 7709057 Disease Relevance 0.09 Pain Relevance 0.86
Apart from activating the body¬ís system of temperature regulation, there is also a hormonal response, which increases body metabolism and the concentrations of adrenaline, noradrenaline, adrenocorticotropic hormone (ACTH), cortisone, pro-opiomelanocortin (POMC), and ?
Positive_regulation (increases) of Phosphorylation (hormone) of ACTH in body associated with noradrenaline
3) Confidence 0.32 Published 2008 Journal Arch Immunol Ther Exp (Warsz) Section Body Doc Link PMC2734249 Disease Relevance 0.14 Pain Relevance 0.30

General Comments

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