INT40190

Context Info Confidence 0.49 First Reported 1984 Last Reported 1984 Negated 1 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.07 Pain Relevance 0.68

extracellular space (IFNA2) extracellular region (IFNA2) cell-cell signaling (IFNA2)

Anatomy Link Frequency neurons 2 IFNA2 (Homo sapiens)

Pain Link Frequency Relevance Heat opiate 3 99.80 Morphine 3 91.28 narcan 4 89.36 analgesia 1 64.76

Disease Link Frequency Relevance Heat Catatonia 1 65.32

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The present observations using the guinea-pig ileum preparation and cortical neurons recording failed to support the hypothesis that alpha-IFN effects are mediated via opiate receptors.

Neg (failed) Positive_regulation (mediated) of Neg (failed) Regulation (effects) of alpha-IFN in neurons associated with opiate

1) Confidence 0.49 Published 1984 Journal Life Sci. Section Abstract Doc Link 6088931 Disease Relevance 0.07 Pain Relevance 0.68

General Comments

This test has worked.