INT40228

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Context Info
Confidence 0.17
First Reported 1984
Last Reported 2007
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.31
Pain Relevance 1.68

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Cck) extracellular region (Cck) DNA binding (Cck)
Cck (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 14 100.00 Very High Very High Very High
Cholecystokinin 9 100.00 Very High Very High Very High
narcan 7 99.66 Very High Very High Very High
medulla 27 99.52 Very High Very High Very High
antagonist 10 98.20 Very High Very High Very High
Endogenous opioid 3 98.08 Very High Very High Very High
vagus nerve 7 89.04 High High
opiate 3 81.00 Quite High
Eae 1 50.32 Quite High
Central nervous system 15 46.04 Quite Low
Disease Link Frequency Relevance Heat
Anorexia 14 80.08 Quite High
Body Weight 3 59.68 Quite High
Obesity 57 56.52 Quite High
Sprains And Strains 5 42.32 Quite Low
Appetite Loss 10 5.00 Very Low Very Low Very Low
Weight Gain 4 5.00 Very Low Very Low Very Low
Stress 4 5.00 Very Low Very Low Very Low
Syndrome 3 5.00 Very Low Very Low Very Low
Hyperphagia 3 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the contrary, naloxone had no apparent effect on the insulin secretory response to the cholinergic agonist carbachol or the synthetic C-terminal octapeptide of cholecystokinin, CCK-8.
Neg (no) Regulation (effect) of Positive_regulation (response) of cholecystokinin associated with agonist, narcan and cholecystokinin
1) Confidence 0.17 Published 1984 Journal Eur. J. Pharmacol. Section Abstract Doc Link 6090153 Disease Relevance 0 Pain Relevance 0.82
This effect of CCK activating POMC "GFP" NTS neurones is blocked by a CCK antagonist and also antagonised by endogenous opioids [89].
Regulation (effect) of Positive_regulation (activating) of CCK associated with medulla, antagonist, endogenous opioid and cholecystokinin
2) Confidence 0.15 Published 2007 Journal Nutr Metab (Lond) Section Body Doc Link PMC2018708 Disease Relevance 0.31 Pain Relevance 0.86

General Comments

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