INT4027

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Context Info
Confidence 0.48
First Reported 1976
Last Reported 1998
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.51
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
bone marrow 2
Salpa1 (Mus musculus)
Pain Link Frequency Relevance Heat
Pain 2 98.10 Very High Very High Very High
abdominal pain 1 92.96 High High
Bile 2 85.20 High High
Analgesic 2 80.20 Quite High
Disease Link Frequency Relevance Heat
Pain 2 98.10 Very High Very High Very High
Abdominal Pain 1 92.96 High High
Choledocholithiasis 1 91.20 High High
Vomiting 1 90.72 High High
Disease 2 89.28 High High
Follicular Lymphoma 1 86.76 High High
Sleep Disorders 1 85.64 High High
Lymphatic System Cancer 4 85.16 High High
Congenital Anomalies 1 79.68 Quite High
INFLAMMATION 2 79.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although abnormal scans were observed with the greatest frequency in patients with bone pain (11 of 11), bone marrow involvement (11 of 12), abnormal skeletal radiographs (11 of 11), and elevated serum alkaline phosphatase levels (5 of 6), bone scanning also detected lymphomatous involvement in patients free of pain or with normal laboratory tests.
Positive_regulation (elevated) of Gene_expression (levels) of serum alkaline phosphatase in bone marrow associated with pain
1) Confidence 0.48 Published 1976 Journal Cancer Section Abstract Doc Link 953962 Disease Relevance 0.92 Pain Relevance 0.19
There was an increase in serum glutamic pyruvic transaminase (SGPT) and serum alkaline phosphatase (SAP) level with the crude extract but stagninol showed no significant changes of serum glutamic oxaloacetic transaminase (SGOT), SGPT and SAP level.
Positive_regulation (increase) of Gene_expression (level) of serum alkaline phosphatase
2) Confidence 0.05 Published 1997 Journal Pharmazie Section Abstract Doc Link 9260269 Disease Relevance 0.24 Pain Relevance 0.16
Laboratory studies disclosed increases in the serum alkaline phosphatase, glutamic oxaloacetic transaminase, glutamic pyruvic transaminase, and serum amylase levels.
Positive_regulation (increases) of Gene_expression (levels) of serum alkaline phosphatase
3) Confidence 0.03 Published 1998 Journal Hepatogastroenterology Section Abstract Doc Link 9840091 Disease Relevance 0.34 Pain Relevance 0.18

General Comments

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