INT4047

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Context Info
Confidence 0.43
First Reported 1976
Last Reported 2010
Negated 2
Speculated 1
Reported most in Abstract
Documents 105
Total Number 106
Disease Relevance 66.54
Pain Relevance 11.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (F13A1) transferase activity, transferring acyl groups (F13A1) cytoplasm (F13A1)
Anatomy Link Frequency
platelet 17
plasma 12
blood 4
coronary artery 3
plaque 2
F13A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Codeine 3 100.00 Very High Very High Very High
eye pain 1 99.92 Very High Very High Very High
Angina 86 99.68 Very High Very High Very High
Inflammatory marker 7 99.56 Very High Very High Very High
aspirin 30 99.24 Very High Very High Very High
Inflammation 105 99.12 Very High Very High Very High
ischemia 29 98.94 Very High Very High Very High
metalloproteinase 39 98.60 Very High Very High Very High
rheumatoid arthritis 76 98.44 Very High Very High Very High
anesthesia 37 98.04 Very High Very High Very High
Disease Link Frequency Relevance Heat
Infection 49 100.00 Very High Very High Very High
Postoperative Complications 1 100.00 Very High Very High Very High
Empyema Thoracis 44 99.92 Very High Very High Very High
Eye Pain 1 99.92 Very High Very High Very High
Obesity 162 99.88 Very High Very High Very High
Thrombocytopenia 6 99.88 Very High Very High Very High
Thrombosis 222 99.80 Very High Very High Very High
Disease 81 99.74 Very High Very High Very High
Coronary Stenosis 3 99.72 Very High Very High Very High
Cv General 3 Under Development 87 99.68 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Fibrin formation during ongoing cutaneous allergic reactions: comparison of responses to antigen and codeine.
Fibrin Binding (formation) of associated with allergic dermatitis, hypersensitivity and codeine
1) Confidence 0.43 Published 1993 Journal J. Allergy Clin. Immunol. Section Title Doc Link 7682581 Disease Relevance 0.20 Pain Relevance 0.29
The most important distinguishing features are encapsulation, intravascular fibrin thrombi, septation, association with other more typical angiolipomas, and occurrence in healthy individuals.
fibrin Binding (association) of associated with angiolipoma
2) Confidence 0.39 Published 1990 Journal Am. J. Surg. Pathol. Section Abstract Doc Link 2294783 Disease Relevance 0.89 Pain Relevance 0.07
F13A1 association with BMI replicates in GenMets study
F13A1 Binding (association) of associated with obesity
3) Confidence 0.36 Published 2010 Journal PLoS Genetics Section Body Doc Link PMC2880558 Disease Relevance 0.81 Pain Relevance 0.03
Immunohistochemistry is variable, but in most cases, staining is positive for CD68, CD4, CD45, HLA-DR, and lysozyme, but negative for S100, CD20, and factor XIIIa [7].
factor XIIIa Binding (negative) of
4) Confidence 0.36 Published 2009 Journal Pediatr Rheumatol Online J Section Body Doc Link PMC2770547 Disease Relevance 1.05 Pain Relevance 0.11
[3 operated cases of congenital deficiency of Factor XIII associated with intracranial hematomas].
Factor XIII Binding (associated) of associated with hematoma
5) Confidence 0.34 Published 1984 Journal No Shinkei Geka Section Title Doc Link 6504254 Disease Relevance 1.17 Pain Relevance 0.12
Many findings indicate a high blood viscosity with resulting capillary occlusion: rapid clotting; low levels of factors I, II, V, VIII, and X; low plasma protein, which may be only 50% of its normal value; thrombocytopenia; and aggregation of white blood cells with fibrin in small lung vessels.
fibrin Binding (aggregation) of in capillary associated with coagulation disorder and thrombocytopenia
6) Confidence 0.30 Published 1987 Journal Anaesthesist Section Abstract Doc Link 3605558 Disease Relevance 0.72 Pain Relevance 0.08
Although intense inflammation was observed as an immediate postoperative complication, fibrin, eye pain and phthisis did not develop in any of the patients.
fibrin Binding (complication) of in eye associated with eye pain, inflammation, pulmonary tuberculosis and postoperative complications
7) Confidence 0.30 Published 2002 Journal Tokai J. Exp. Clin. Med. Section Abstract Doc Link 12472167 Disease Relevance 0.74 Pain Relevance 0.15
At laparoscopic exploration, a chylous leak within the gallbladder fossa was controlled with suture ligation and fibrin glue with immediate resolution of the leak.
fibrin Binding (ligation) of in suture
8) Confidence 0.30 Published 2006 Journal Am Surg Section Abstract Doc Link 16494185 Disease Relevance 0.34 Pain Relevance 0.09
Platelet aggregation within the stenosis is responsible for the primary flow obstruction, but fibrin subsequently enmeshes the platelets and thus stabilizes the thrombus.
fibrin Binding (stabilizes) of in platelets associated with pathologic constriction and thrombosis
9) Confidence 0.30 Published 1991 Journal Am. J. Cardiol. Section Abstract Doc Link 1892065 Disease Relevance 1.58 Pain Relevance 0
Platelet aggregation within the stenosis is responsible for the primary flow obstruction, but fibrin subsequently enmeshes the platelets and thus stabilizes the thrombus.
fibrin Binding (enmeshes) of in platelets associated with pathologic constriction and thrombosis
10) Confidence 0.30 Published 1991 Journal Am. J. Cardiol. Section Abstract Doc Link 1892065 Disease Relevance 1.51 Pain Relevance 0
Catheters are associated with a number of recognized complications, including infection, catheter-associated fibrin sheath and thrombus leading to malfunction, central venous stenosis, and right atrial thrombus.
fibrin Binding (recognized) of associated with pathologic constriction, thrombosis and infection
11) Confidence 0.29 Published 2010 Journal Am. J. Kidney Dis. Section Abstract Doc Link 19800723 Disease Relevance 0.81 Pain Relevance 0.06
Thrombus formation, based on platelet activation and aggregation as well as fibrin formation, is the main consequence of plaque disruption.
fibrin Binding (formation) of in plaque associated with thrombosis
12) Confidence 0.29 Published 1999 Journal Acta Med. Austriaca Section Abstract Doc Link 10478281 Disease Relevance 1.00 Pain Relevance 0.13
Fibrin glue (Tissucol Duo Quick®) is a tissue adhesive composed of two components which mimics the natural fibrin formation.
fibrin Binding (formation) of
13) Confidence 0.26 Published 2008 Journal Korean Journal of Ophthalmology : KJO Section Body Doc Link PMC2629906 Disease Relevance 0.45 Pain Relevance 0
Binding of activated platelets, white blood cells and fibrin to the artificial surfaces was quantified by means of antibody binding and histological validation was achieved by scanning electron microscopy.
fibrin Binding (Binding) of in white blood cells
14) Confidence 0.24 Published 2006 Journal Perfusion Section Abstract Doc Link 16817289 Disease Relevance 0.22 Pain Relevance 0.10
Ex vivo assays for fibrin clot permeation, fiber thickness, factor XIII cross-linking activity, and fibrinolysis were performed on the plasma of the above subjects.
fibrin Binding (cross) of in plasma
15) Confidence 0.22 Published 2008 Journal J. Vasc. Surg. Section Body Doc Link 18829228 Disease Relevance 0.15 Pain Relevance 0
Furthermore, LPS-induced thrombin generation increased plasma levels of circulating polymerized, but not cross-linked, fibrin (ie, thrombus precursor protein), whereas levels of soluble fibrin were unaffected.
fibrin Neg (not) Binding (cross-linked) of in plasma associated with thrombosis
16) Confidence 0.19 Published 1999 Journal Arterioscler. Thromb. Vasc. Biol. Section Abstract Doc Link 10521382 Disease Relevance 0.15 Pain Relevance 0.48
The intrapulmonary aggregation of platelets and fibrin was monitored by external detection of radioactivity arising from pretrauma intravenous injection of 51Cr-labeled platelets and 125I-labeled fibrinogen.
fibrin Binding (aggregation) of in external
17) Confidence 0.14 Published 1985 Journal J Trauma Section Abstract Doc Link 3989886 Disease Relevance 0.58 Pain Relevance 0.10
These wounds were covered by sheets of cultured epidermal graft (group A), cultured epidermal graft with collagen dermis and fibrin (group B), cultured epidermal graft with collagen dermis (group C), or cultured epidermal graft with fibrin (group D).
fibrin Binding (graft) of in dermis associated with injury
18) Confidence 0.11 Published 1999 Journal Ann Plast Surg Section Abstract Doc Link 10560869 Disease Relevance 0.32 Pain Relevance 0.10
Our hypothesis was that healing would be better after treatment with HBO plus fibrin than with fibrin or HBO alone; therefore, our analysis only compared the HBO plus fibrin group with the other 3 groups.
fibrin Binding (group) of
19) Confidence 0.10 Published 2010 Journal J Orthop Surg Res Section Body Doc Link PMC3018382 Disease Relevance 0 Pain Relevance 0
The beneficial effects of a moist versus a dry wound environment include: prevention of tissue dehydration and cell death, accelerated angiogenesis, increased breakdown of dead tissue and fibrin, i.e., pericapillary fibrin cuffs, and potentiating the interaction of growth factors with their target cells.
fibrin Binding (interaction) of associated with volume depletion and dehydration, injury and death
20) Confidence 0.10 Published 1994 Journal Am. J. Surg. Section Abstract Doc Link 8109679 Disease Relevance 0.98 Pain Relevance 0.10

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