INT4065

Context Info Confidence 0.02 First Reported 1976 Last Reported 2001 Negated 0 Speculated 0 Reported most in Title Documents 4 Total Number 4 Disease Relevance 1.33 Pain Relevance 0.72

Anatomy Link Frequency blood 3 head 1 cerebral blood flow (Mus musculus)

Pain Link Frequency Relevance Heat depression 1 94.80 isoflurane 1 90.52 Opioid 1 88.48 anesthesia 4 84.64 cINOD 1 75.68 opiate 3 75.00 withdrawal 1 75.00 imagery 2 26.48 cocaine 1 25.00

Disease Link Frequency Relevance Heat Hypoxia 11 99.02 Opiate Addiction 1 98.28 Depression 1 94.80 Head Trauma 1 93.72 Paralysis 1 92.36 Sleep Disorders 2 85.44 Nicotine Addiction 1 76.40 Disease 1 75.00 Cerebrovascular Disease 1 42.24 Increased Venous Pressure Under Development 2 33.20

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The purpose of this study was to determine if cerebral blood flow (CBF) alterations are associated with discontinuation of heroin in chronic heroin users, and whether these alterations are reversible during abstinence.

cerebral blood flow Binding (associated) of in blood associated with opiate addiction

1) Confidence 0.02 Published 1996 Journal Psychiatry Res Section Abstract Doc Link 8797241 Disease Relevance 0.10 Pain Relevance 0.27

The effects of diazepam on cerebral blood flow and oxygen consumption in rats and its synergistic interaction with nitrous oxide.

cerebral blood flow Binding (interaction) of in blood

2) Confidence 0.00 Published 1976 Journal Anesthesiology Section Title Doc Link 962180 Disease Relevance 0.18 Pain Relevance 0.22

Crawford (1996, 1998) proposes an association between AD and cerebral blood flow (CBF) by citing evidence that many of the factors that are linked with an increased risk of AD also decrease CBF (e.g., old age, depression, underactivity, head trauma).

cerebral blood flow Binding (association) of in head associated with depression and head trauma

3) Confidence 0.00 Published 2001 Journal Int. Rev. Neurobiol. Section Abstract Doc Link 11526738 Disease Relevance 0.34 Pain Relevance 0.12

Hypoxia, alpha 2-adrenergic, and nitric oxide-dependent interactions on canine cerebral blood flow.

cerebral blood flow Binding (interactions) of in blood associated with hypoxia

4) Confidence 0.00 Published 1994 Journal Am. J. Physiol. Section Title Doc Link 7511347 Disease Relevance 0.71 Pain Relevance 0.11

General Comments

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