INT40712

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Context Info
Confidence 0.78
First Reported 1981
Last Reported 2004
Negated 3
Speculated 0
Reported most in Abstract
Documents 9
Total Number 9
Disease Relevance 5.93
Pain Relevance 3.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (EPX)
Anatomy Link Frequency
endometrium 4
nerve 1
eosinophil 1
EPX (Homo sapiens)
Pain Link Frequency Relevance Heat
endometriosis 24 100.00 Very High Very High Very High
depression 21 100.00 Very High Very High Very High
Action potential 6 99.44 Very High Very High Very High
narcan 9 98.92 Very High Very High Very High
chemokine 5 91.00 High High
dexamethasone 1 84.00 Quite High
Sciatic nerve 3 83.00 Quite High
opiate 9 75.00 Quite High
epidural 4 75.00 Quite High
pain pelvic 4 70.48 Quite High
Disease Link Frequency Relevance Heat
Endometriosis (extended) 24 100.00 Very High Very High Very High
Depression 21 100.00 Very High Very High Very High
Cancer 10 94.96 High High
Hypersensitivity 10 87.92 High High
Recurrence 5 87.76 High High
Eosinophilia 31 87.60 High High
Occupational Lung Diseases 1 87.20 High High
Disease 33 81.08 Quite High
Attention Deficit Hyperactivity Disorder 1 80.88 Quite High
Reprotox - General 3 4 70.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A marker, eosinophil peroxidase (EPO), has been identified that is expressed in ~90% of endometriosis specimens, and is not expressed or only weakly expressed in normal endometrium.
Gene_expression (expressed) of EPO in endometrium associated with endometriosis
1) Confidence 0.78 Published 2001 Journal Expert Rev Mol Med Section Abstract Doc Link 14585151 Disease Relevance 0.97 Pain Relevance 0.31
A marker, eosinophil peroxidase (EPO), has been identified that is expressed in ~90% of endometriosis specimens, and is not expressed or only weakly expressed in normal endometrium.
Gene_expression (expressed) of eosinophil peroxidase in endometrium associated with endometriosis
2) Confidence 0.78 Published 2001 Journal Expert Rev Mol Med Section Abstract Doc Link 14585151 Disease Relevance 0.98 Pain Relevance 0.31
A marker, eosinophil peroxidase (EPO), has been identified that is expressed in ~90% of endometriosis specimens, and is not expressed or only weakly expressed in normal endometrium.
Neg (not) Gene_expression (expressed) of EPO in endometrium associated with endometriosis
3) Confidence 0.78 Published 2001 Journal Expert Rev Mol Med Section Abstract Doc Link 14585151 Disease Relevance 0.99 Pain Relevance 0.32
The results suggest that 1) EPP is positive and fluctuates with ventilation and arterial pulsations, 2) intraperitoneum insufflation produces an increase in EPP that lasts until the procedure is discontinued, and 3) increased intrathoracic and intraperitoneal pressures play a predominant role in producing the elevation of EPP.
Gene_expression (producing) of EPP
4) Confidence 0.77 Published 1997 Journal Masui Section Abstract Doc Link 9128019 Disease Relevance 0 Pain Relevance 0.04
A marker, eosinophil peroxidase (EPO), has been identified that is expressed in ~90% of endometriosis specimens, and is not expressed or only weakly expressed in normal endometrium.
Neg (not) Gene_expression (expressed) of eosinophil peroxidase in endometrium associated with endometriosis
5) Confidence 0.68 Published 2001 Journal Expert Rev Mol Med Section Abstract Doc Link 14585151 Disease Relevance 0.99 Pain Relevance 0.32
The depression of the EPP was partly antagonized by naloxone (3 X 10(-8) M).
Gene_expression (depression) of EPP associated with depression and narcan
6) Confidence 0.56 Published 1981 Journal Arch Int Pharmacodyn Ther Section Abstract Doc Link 6114716 Disease Relevance 0.51 Pain Relevance 0.74
Meperidine also depressed the EPP produced by iontophoresis of acetylcholine onto the endplate, but this depression was not antagonized by naloxone.
Gene_expression (produced) of EPP associated with depression and narcan
7) Confidence 0.50 Published 1981 Journal Arch Int Pharmacodyn Ther Section Abstract Doc Link 6114716 Disease Relevance 0.52 Pain Relevance 0.77
When the nerve terminal action potential and the endplate potential (EPP) were recorded simultaneously, the EPP was depressed by meperidine but only a small and variable decrease in the nerve terminal action potential was observed which did not produce the EPP depression.
Neg (not) Gene_expression (produce) of EPP in nerve associated with action potential and depression
8) Confidence 0.50 Published 1981 Journal Arch Int Pharmacodyn Ther Section Abstract Doc Link 6114716 Disease Relevance 0.50 Pain Relevance 0.72
After short term treatment with glucocorticoids a significant decrease in the levels of serum eosinophil cationic protein (ECP) and serum eosinophil peroxidase was observed [43].
Gene_expression (levels) of eosinophil peroxidase in eosinophil
9) Confidence 0.04 Published 2004 Journal Clin Mol Allergy Section Body Doc Link PMC425596 Disease Relevance 0.47 Pain Relevance 0.09

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