INT40772

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.25
First Reported 1980
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 0.49
Pain Relevance 2.75

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Iars) translation (Iars) ligase activity (Iars)
cytoplasm (Iars)
Anatomy Link Frequency
tube 1
Iars (Mus musculus)
Pain Link Frequency Relevance Heat
Somatostatin 35 100.00 Very High Very High Very High
Calcium channel 10 98.44 Very High Very High Very High
sodium channel 5 96.80 Very High Very High Very High
tetrodotoxin 5 96.08 Very High Very High Very High
MU agonist 4 95.28 Very High Very High Very High
Chronic pancreatitis 2 91.88 High High
agonist 8 87.92 High High
Opioid 23 74.32 Quite High
antagonist 14 38.48 Quite Low
Enkephalin 2 14.00 Low Low
Disease Link Frequency Relevance Heat
Glioma 13 100.00 Very High Very High Very High
Diabetes Mellitus 3 93.32 High High
Pancreatitis 2 91.88 High High
Drug Dependence 1 8.56 Low Low
Bordatella Infection 1 5.00 Very Low Very Low Very Low
Adhesions 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The immunoreactive somatostatin (IRS) released into the medium during a treatment epoch was compared to the amount released from the same cells during an immediately preceding control period.
Localization (released) of IRS associated with somatostatin
1) Confidence 0.25 Published 1982 Journal Endocrinology Section Abstract Doc Link 6120071 Disease Relevance 0 Pain Relevance 0.41
The immunoreactive somatostatin (IRS) released into the medium during a treatment epoch was compared to the amount released from the same cells during an immediately preceding control period.
Localization (released) of IRS associated with somatostatin
2) Confidence 0.23 Published 1982 Journal Endocrinology Section Abstract Doc Link 6120071 Disease Relevance 0 Pain Relevance 0.41
These findings indicate that IRS release by cerebral cortical cells is stimulated by membrane depolarization and is dependent on both Na+ and Ca++ entry into the cells.
Localization (release) of IRS associated with somatostatin
3) Confidence 0.22 Published 1982 Journal Endocrinology Section Abstract Doc Link 6120071 Disease Relevance 0 Pain Relevance 0.52
Depolarization by veratridine, a sodium ionophore, also stimulated IRS release.
Localization (release) of IRS associated with somatostatin
4) Confidence 0.22 Published 1982 Journal Endocrinology Section Abstract Doc Link 6120071 Disease Relevance 0 Pain Relevance 0.52
Potassium (60 mM) induced an increase in IRS secretion which was dependent on extracellular calcium concentration and could be prevented by the addition of the calcium channel blockers, cobalt or verapamil.
Localization (secretion) of IRS associated with calcium channel and somatostatin
5) Confidence 0.19 Published 1982 Journal Endocrinology Section Abstract Doc Link 6120071 Disease Relevance 0 Pain Relevance 0.49
Additional studies showed that the two RTKs, which are present in C6 glioma cells, IRs and PDGFRs, had no apparent role on ERK activation by a ?
Localization (present) of IRs associated with glioma
6) Confidence 0.12 Published 2002 Journal BMC Pharmacol Section Body Doc Link PMC88976 Disease Relevance 0.19 Pain Relevance 0.25
Exocrine pancreatic secretion and plasma immunoreactive secretin (IRS) levels have been simultaneously observed in response to intraduodenal infusion of 1-phenyl-1-hydroxy-n-pentane (PHP) and 0.1 N HCl in normal subjects, patients with diabetes mellitus and patients with chronic pancreatitis by use of this tube. (1) Pancreatic flow rate and bicarbonate concentration were found to increase to twice those of basal levels and plasma IRS levels rose significantly after infusion of PHP or HCl in normal subjects.
Localization (secretion) of IRS in tube associated with diabetes mellitus and chronic pancreatitis
7) Confidence 0.06 Published 1980 Journal Tohoku J. Exp. Med. Section Abstract Doc Link 7466802 Disease Relevance 0.30 Pain Relevance 0.14

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox