INT40906

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Context Info
Confidence 0.43
First Reported 1982
Last Reported 1982
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0
Pain Relevance 1.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Adra2c) cytoplasm (Adra2c) signal transducer activity (Adra2c)
Adra2c (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 6 100.00 Very High Very High Very High
Intracerebroventricular 2 99.72 Very High Very High Very High
Potency 4 98.60 Very High Very High Very High
Clonidine 12 98.24 Very High Very High Very High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Intracerebroventricular injection of alpha-adrenoceptor agonists reduced gastric secretion, in the following order (relative potency, clonidine = 1): oxymetazoline (100) greater than clonidine (1) greater than methoxamine (0.024) greater than phenylephrine (0.003).
Negative_regulation (reduced) of Localization (secretion) of alpha-adrenoceptor associated with agonist, intracerebroventricular, clonidine and potency
1) Confidence 0.43 Published 1982 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 6126820 Disease Relevance 0 Pain Relevance 0.66
Subcutaneous injection of alpha-adrenoceptor agonists also reduced gastric secretion, in the following order (relative potency, clonidine = 1): clonidine (1) greater than oxymetazoline (0.3), much greater than phenylephrine (0.001) approximately methoxamine (0.0006).
Negative_regulation (reduced) of Localization (secretion) of alpha-adrenoceptor associated with agonist, clonidine and potency
2) Confidence 0.43 Published 1982 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 6126820 Disease Relevance 0 Pain Relevance 0.80

General Comments

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