INT4099

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Context Info
Confidence 0.17
First Reported 1976
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.09
Pain Relevance 0.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Antxr1)
Anatomy Link Frequency
nerve 1
Antxr1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
sodium channel 5 99.80 Very High Very High Very High
tetrodotoxin 12 97.44 Very High Very High Very High
Root ganglion neuron 1 94.60 High High
Neurotransmitter 3 91.32 High High
antagonist 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 1 94.28 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Electrophysiological analysis of the effects of scorpion toxin I, one of the neurotoxins from the venom of the scorpion Androctonus australis Hector, upon crayfish neuromuscular junctions has shown that the toxin strongly associates with the nerve terminal to stimulate release of neurotransmitters.
Regulation (effects) of scorpion toxin I in nerve associated with neurotransmitter
1) Confidence 0.17 Published 1976 Journal Biochim. Biophys. Acta Section Abstract Doc Link 974149 Disease Relevance 0 Pain Relevance 0.08
This toxin seems to be a site I toxin affecting the sodium channel through a mechanism quite similar to that of TTX: it suppresses the peak sodium current without altering the activation or inactivation kinetics.
Regulation (affecting) of I toxin associated with tetrodotoxin and sodium channel
2) Confidence 0.00 Published 2002 Journal J. Biol. Chem. Section Abstract Doc Link 12228241 Disease Relevance 0.09 Pain Relevance 0.89

General Comments

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