INT41136

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Context Info
Confidence 0.37
First Reported 1980
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.66
Pain Relevance 2.45

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Gip) extracellular region (Gip) cytoplasm (Gip)
Anatomy Link Frequency
plasma 2
fat 2
Gip (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Somatostatin 12 99.96 Very High Very High Very High
Enkephalin 20 99.50 Very High Very High Very High
Chronic pancreatitis 3 87.84 High High
narcan 6 85.28 High High
tolerance 2 83.00 Quite High
Endogenous opioid 2 63.12 Quite High
Disease Link Frequency Relevance Heat
Body Weight 2 91.72 High High
Steatorrhea 3 89.72 High High
Pancreatitis 3 87.84 High High
Diabetes Mellitus 12 84.08 Quite High
Impaired Glucose Tolerance 3 83.00 Quite High
Obesity 3 75.44 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both methionine- and leucine-enkephalins caused a dose-dependent inhibition of gastric inhibitory polypeptide (GIP) stimulated SLI secretion.
Negative_regulation (inhibition) of Positive_regulation (stimulated) of gastric inhibitory polypeptide associated with somatostatin and enkephalin
1) Confidence 0.37 Published 1983 Journal Can. J. Physiol. Pharmacol. Section Abstract Doc Link 6137272 Disease Relevance 0 Pain Relevance 1.07
Both methionine- and leucine-enkephalins caused a dose-dependent inhibition of gastric inhibitory polypeptide (GIP) stimulated SLI secretion.
Negative_regulation (inhibition) of Positive_regulation (stimulated) of GIP associated with somatostatin and enkephalin
2) Confidence 0.37 Published 1983 Journal Can. J. Physiol. Pharmacol. Section Abstract Doc Link 6137272 Disease Relevance 0 Pain Relevance 1.07
After restoration of the GIP response to fat by pancreatin, the inhibitory effect of IV glucose on fat-induced GIP increase was restored.
Negative_regulation (effect) of Positive_regulation (increase) of GIP in fat
3) Confidence 0.34 Published 1980 Journal Diabetologia Section Abstract Doc Link 6997121 Disease Relevance 0.53 Pain Relevance 0.23
In contrast, the late-phase (20-120 min) plasma insulin response to GIP was attenuated, compared with the plasma insulin response to GLP-1, in all five groups.
Negative_regulation (attenuated) of Positive_regulation (response) of GIP in plasma
4) Confidence 0.06 Published 2003 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 14557471 Disease Relevance 1.13 Pain Relevance 0.07

General Comments

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