INT41270

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.68
First Reported 1984
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 6
Disease Relevance 2.08
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (Srr) lyase activity (Srr) plasma membrane (Srr)
cellular amino acid metabolic process (Srr) cytoplasm (Srr)
Anatomy Link Frequency
pinealocytes 3
brain 1
dendritic cells 1
Srr (Mus musculus)
Pain Link Frequency Relevance Heat
cINOD 3 95.76 Very High Very High Very High
Potency 1 90.24 High High
Inflammation 12 72.48 Quite High
Inflammatory response 1 65.04 Quite High
imagery 10 5.00 Very Low Very Low Very Low
Glutamate 9 5.00 Very Low Very Low Very Low
Neurotransmitter 6 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
noradrenaline 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anaphylaxis 2 100.00 Very High Very High Very High
Metastasis 35 99.26 Very High Very High Very High
INFLAMMATION 14 94.32 High High
Arthus Reaction 2 90.32 High High
Increased Venous Pressure Under Development 1 87.92 High High
Non-small-cell Lung Cancer 10 86.80 High High
Measles 4 78.92 Quite High
Hypersensitivity 4 75.00 Quite High
Respiratory Syncytial Virus 94 72.16 Quite High
Disease 17 68.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As for the release of anaphylactic mediators, suprofen was less potent than tranilast in terms of histamine release, but not the release of the slow reacting substance of anaphylaxis (SRS-A).
Localization (release) of SRS associated with anaphylaxis
1) Confidence 0.68 Published 1984 Journal Jpn. J. Pharmacol. Section Abstract Doc Link 6143845 Disease Relevance 0.78 Pain Relevance 0.36
Potentially, once N SRS are internalized and processed by dendritic cells, the bacterial RNA they contain, could be made accessible for cellular receptors such as TLR7 or TLR8 and provide the signaling for maturation [34].
Localization (internalized) of N SRS in dendritic cells
2) Confidence 0.45 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2262139 Disease Relevance 0.54 Pain Relevance 0.03
To investigate whether RIBEYE was specifically localized at pinealocyte SRs, postembedding immunogold electron microscopy was performed with antibodies against the A- and B-domains of RIBEYE.
Localization (localized) of SRs in pinealocyte
3) Confidence 0.37 Published 2008 Journal Cell Tissue Res Section Body Doc Link PMC2757586 Disease Relevance 0 Pain Relevance 0
m (e–h)Fig. 3Association of SRs with RIBEYE and CtBP1 in rat pinealocytes under light and dark conditions. a, b As seen in the merged image (merge) of the high power confocal laser-scanning images, RIBEYE-B-labeled (RIB B) SRs (red) completely co-localize (examples marked by arrowheads) with RIBEYE A (RIB A; green), irrespective of day (a) or night (b) conditions.
Localization (localize) of SRs in pinealocytes
4) Confidence 0.34 Published 2008 Journal Cell Tissue Res Section Body Doc Link PMC2757586 Disease Relevance 0 Pain Relevance 0
However, the localization of SRs near the cell membrane, their topographical relationship to neighboring pinealocytes, and their characteristic morphological changes under various conditions support an involvement of pineal SRs in transmitter release and intercellular communication (Vollrath 1981; McNulty and Fox 1992; Vollrath and Spiwoks-Becker 2002).
Localization (localization) of SRs in pinealocytes
5) Confidence 0.32 Published 2008 Journal Cell Tissue Res Section Body Doc Link PMC2757586 Disease Relevance 0 Pain Relevance 0
As a result of these trials, RPA class I patients with a single brain metastasis are currently treated with surgical resection or SRS followed by whole-brain radiation.
Localization (resection) of SRS in brain associated with metastasis
6) Confidence 0.24 Published 2007 Journal International Journal of Nanomedicine Section Body Doc Link PMC2673824 Disease Relevance 0.76 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox