INT41314

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Context Info
Confidence 0.59
First Reported 1984
Last Reported 2009
Negated 0
Speculated 1
Reported most in Abstract
Documents 9
Total Number 10
Disease Relevance 5.61
Pain Relevance 1.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
Liver 2
platelet 2
upper 1
kidney 1
GGTLC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Paracetamol 4 98.32 Very High Very High Very High
abdominal pain 6 96.68 Very High Very High Very High
Pain 3 95.96 Very High Very High Very High
Analgesic 2 95.72 Very High Very High Very High
headache 1 94.04 High High
cocaine 2 90.12 High High
alcohol 5 88.40 High High
medulla 13 86.84 High High
Bile 26 85.88 High High
lidocaine 1 75.88 Quite High
Disease Link Frequency Relevance Heat
Budd-chiari Syndrome 1 99.68 Very High Very High Very High
Hepatitis C Virus Infection 18 99.24 Very High Very High Very High
Bronchitis 1 99.00 Very High Very High Very High
Common Cold 1 98.56 Very High Very High Very High
Acute Liver Failure 1 98.44 Very High Very High Very High
Hyperbilirubinemia 1 98.42 Very High Very High Very High
Hepatitis 8 98.08 Very High Very High Very High
Jaundice 5 96.92 Very High Very High Very High
Abdominal Pain 6 96.68 Very High Very High Very High
Vomiting 1 96.36 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The levels of gamma-glutamyl transpeptidase for workers reluctant to work under tanshin funin and workers who spent less than two years in tanshin funin increased significantly from the fiscal year 1997 to year 2001 (46.7 to 67.5 IU/l, p<0.001, and 36.9 to 72.4 IU/l, p=0.005, respectively), although those of their matched regular workers did not show significant changes.
Gene_expression (levels) of gamma-glutamyl transpeptidase
1) Confidence 0.59 Published 2006 Journal J Occup Health Section Abstract Doc Link 16612040 Disease Relevance 0.62 Pain Relevance 0.13
Coinfected patients presented higher platelet counts, but aminotransferase and gamma-glutamyl transpeptidase levels were higher among HCV-infected subjects.
Gene_expression (levels) of gamma-glutamyl transpeptidase in platelet associated with hepatitis c virus infection
2) Confidence 0.50 Published 2009 Journal Rev. Soc. Bras. Med. Trop. Section Abstract Doc Link 19802468 Disease Relevance 0.94 Pain Relevance 0.18
Coinfected patients presented higher platelet counts, but aminotransferase and gamma-glutamyl transpeptidase levels were higher among HCV-infected subjects.
Gene_expression (counts) of gamma-glutamyl transpeptidase in platelet associated with hepatitis c virus infection
3) Confidence 0.50 Published 2009 Journal Rev. Soc. Bras. Med. Trop. Section Abstract Doc Link 19802468 Disease Relevance 0.96 Pain Relevance 0.19
Liver function analyte levels were measured, including albumin, total protein, aspartate aminotransferase, and alanine transaminase, alkaline phosphatase, gamma-glutamyl transpeptidase, and total bilirubin.
Gene_expression (measured) of gamma-glutamyl transpeptidase in Liver
4) Confidence 0.32 Published 2004 Journal Plast. Reconstr. Surg. Section Abstract Doc Link 15318060 Disease Relevance 0.47 Pain Relevance 0.08
Serum gamma-glutamyl transpeptidase activity was raised in all cases, alkaline phosphatase in 94.6%, and less frequently lactate dehydrogenase (80%), SGPT (84.7%), and SGOT (76%).
Gene_expression (raised) of gamma-glutamyl transpeptidase
5) Confidence 0.15 Published 1984 Journal Hepatology Section Abstract Doc Link 6693064 Disease Relevance 1.25 Pain Relevance 0.14
Laboratory findings showed elevated total bilirubin, alkaline phosphatase, gamma-glutamyl transpeptidase, and C-reactive protein levels.
Gene_expression (levels) of gamma-glutamyl transpeptidase
6) Confidence 0.09 Published 2009 Journal Surg. Today Section Abstract Doc Link 19280287 Disease Relevance 0.38 Pain Relevance 0.13
Liver function tests found the following concentrations: total bilirubin, 27.5 mg/dL (normal [nl] range, 0.3-1.2 mg/dL); aspartate aminotransferase, 151 IU/L (nl, 13-33 IU/L); alkaine aminotransferase, 470 IU/L (nl, 8-42 IU/L); alkaline phosphatase, 1082 IU/L (n1, 115-359 IUAL); and gamma-glutamyl transpeptidase, 795 IU/L (nl, 10-47 IU/L) indicative of intrahepatic cholestasis.
Spec (found) Gene_expression (found) of gamma-glutamyl transpeptidase in Liver
7) Confidence 0.09 Published 2008 Journal Clin Ther Section Body Doc Link 19167598 Disease Relevance 0 Pain Relevance 0
Low GSH concentrations, as well as low activities of glutathione reductase, GPx -I, GPx -II, and gamma-glutamyl transpeptidase, may therefore render the inner medullary region of kidney particularly vulnerable to paracetamol-related analgesic nephropathy.
Gene_expression (concentrations) of gamma-glutamyl transpeptidase in kidney associated with paracetamol, analgesic and renal disease
8) Confidence 0.04 Published 1984 Journal Biochem. Pharmacol. Section Abstract Doc Link 6145422 Disease Relevance 0.17 Pain Relevance 0.82
METHODS: Serum levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), total bilirubin (TBil), alkaline phosphatase (ALP), gamma-glutamyl transpeptidase (GTP), and lactate dehydrogenase (LDH) were measured before and 1,2,3,7, and 14 days after anesthesia in each of 60 patients receiving either sevoflurane or isoflurane anesthesia for neurosurgery (tumor resection).
Gene_expression (levels) of gamma-glutamyl transpeptidase
9) Confidence 0.03 Published 1999 Journal Acta Anaesthesiol Scand Section Body Doc Link 10081544 Disease Relevance 0 Pain Relevance 0
Hyperbilirubinemia (total bilirubin > 1.2 mg/dL) was evident in 30 patients (76.9%) and elevated levels of Alkaline Phosphatase and Gamma Glutamyl Transpeptidase (ALP > 230 IU/L, GGT > 48 IU/L) were found in all cases except one (97.4%) who was diagnosed incidentally during the upper gastrointestinal endoscopy.


Gene_expression (levels) of Gamma Glutamyl Transpeptidase in upper associated with hyperbilirubinemia
10) Confidence 0.01 Published 2007 Journal BMC Gastroenterol Section Body Doc Link PMC1933541 Disease Relevance 0.81 Pain Relevance 0.12

General Comments

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