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Context Info
Confidence 0.53
First Reported 1984
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.06
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Cd2) cell adhesion (Cd2) protein complex (Cd2)
Anatomy Link Frequency
bone marrow 1
T cell 1
Cd2 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 17 67.12 Quite High
cytokine 3 65.48 Quite High
chemokine 2 65.04 Quite High
Pain 11 47.08 Quite Low
depression 9 43.68 Quite Low
Inflammation 7 42.00 Quite Low
abdominal pain 1 41.20 Quite Low
tetrodotoxin 1 39.44 Quite Low
pruritus 9 38.60 Quite Low
headache 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Systemic Mastocytosis 39 97.06 Very High Very High Very High
Cutaneous Mastocytosis 24 93.76 High High
Exanthema 1 88.08 High High
Urticaria Pigmentosa 1 87.44 High High
Mast Cell Leukemia 4 80.76 Quite High
Disease 16 78.60 Quite High
Mastocytosis 89 71.32 Quite High
Hypoxia 1 56.64 Quite High
Hypotension 2 48.48 Quite Low
Aggression 1 47.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the absence of [Ca]0, Cd2+ frequently produced twitching in several fibers, which caused dislodgement of the micro-electrode.
Gene_expression (produced) of Cd2
1) Confidence 0.53 Published 1984 Journal Arch Int Pharmacodyn Ther Section Abstract Doc Link 6149733 Disease Relevance 0.06 Pain Relevance 0
Minor criteria for a diagnosis of SM can include abnormal mast cell morphologies in the bone marrow and other extracutaneous organs, mutation of the tyrosine kinase KIT at codon 816, expression of CD2 and/or CD25 by bone marrow mast cells, and a serum tryptase level >20 ng/mL.
Gene_expression (expression) of CD2 in bone marrow associated with systemic mastocytosis
2) Confidence 0.49 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2386235 Disease Relevance 2.00 Pain Relevance 0.06
Human EC express CD40, CD58 (LFA-3), CD134 (OX40) ligand and ICOS ligand, which can contribute to T cell activation in vitro [21-23].
Gene_expression (express) of LFA-3 in T cell
3) Confidence 0.05 Published 2004 Journal BMC Immunol Section Body Doc Link PMC394319 Disease Relevance 0 Pain Relevance 0.10

General Comments

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