INT41515

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Context Info
Confidence 0.51
First Reported 1980
Last Reported 1997
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.37
Pain Relevance 1.73

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (CELA1) extracellular region (CELA1)
CELA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 26 99.84 Very High Very High Very High
tolerance 2 93.92 High High
imagery 1 86.60 High High
fibrosis 1 48.56 Quite Low
Disease Link Frequency Relevance Heat
Pancreatitis 26 99.84 Very High Very High Very High
Body Weight 1 96.12 Very High Very High Very High
Impaired Glucose Tolerance 2 94.56 High High
Stress 4 93.08 High High
Diabetes Mellitus 4 84.48 Quite High
Frailty 1 50.88 Quite High
Fibrosis 1 48.56 Quite Low
Disease 1 31.76 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Fecal concentrations of elastase-1 were also clearly reduced in chronic pancreatitis (p < 0.0001).
Negative_regulation (reduced) of elastase-1 associated with chronic pancreatitis
1) Confidence 0.51 Published 1997 Journal Pancreas Section Abstract Doc Link 9260205 Disease Relevance 0.58 Pain Relevance 0.62
In PDL rats at 2, 4, and 8 weeks after ligation, serum elastase levels had significantly decreased, whereas amylase levels had not changes significantly when compared with the control rats.
Negative_regulation (decreased) of elastase
2) Confidence 0.03 Published 1980 Journal Gastroenterol. Jpn. Section Abstract Doc Link 6161056 Disease Relevance 0.25 Pain Relevance 0.25
In the CP group, pancreatic contents of protein, amylase, elastase, and lipase significantly decreased to 64, 38, 23, and 68% of the control group, respectively.
Negative_regulation (decreased) of elastase associated with chronic pancreatitis
3) Confidence 0.00 Published 1995 Journal Dig. Dis. Sci. Section Abstract Doc Link 7587814 Disease Relevance 1.54 Pain Relevance 0.86

General Comments

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