INT41521

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Context Info
Confidence 0.36
First Reported 1980
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 5
Disease Relevance 0.74
Pain Relevance 1.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Cndp2) peptidase activity (Cndp2) cytoplasm (Cndp2)
Cndp2 (Mus musculus)
Pain Link Frequency Relevance Heat
Analgesic 3 100.00 Very High Very High Very High
antagonist 2 98.80 Very High Very High Very High
Central nervous system 2 98.68 Very High Very High Very High
Antinociceptive 1 97.64 Very High Very High Very High
Cholecystokinin 4 95.84 Very High Very High Very High
Neurotransmitter 4 92.92 High High
Morphine 2 92.80 High High
Neuropeptide 2 91.60 High High
Opioid 3 90.60 High High
Endogenous opioid 1 81.28 Quite High
Disease Link Frequency Relevance Heat
Anaemia 2 99.04 Very High Very High Very High
Syndrome 2 97.56 Very High Very High Very High
Protozoal Infection 2 97.36 Very High Very High Very High
Disease 6 94.64 High High
Experimental Autoimmune Neuritis 4 75.00 Quite High
Cyst 2 72.72 Quite High
Rickets 2 65.92 Quite High
Targeted Disruption 6 50.84 Quite High
Helminth Infection 2 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Insect M13 peptidases are associated with metamorphosis [26,27] and immunity to bacterial, fungal and protozoan infections [28,29].
peptidase Binding (associated) of associated with protozoal infection
1) Confidence 0.36 Published 2008 Journal BMC Evol Biol Section Body Doc Link PMC2259306 Disease Relevance 0.17 Pain Relevance 0.14
Invertebrate M13 peptidases have been found in organisms ranging from Hydra vulgaris through to highly derived insects such as Drosophila melanogaster.
peptidase Binding (found) of
2) Confidence 0.36 Published 2008 Journal BMC Evol Biol Section Body Doc Link PMC2259306 Disease Relevance 0.41 Pain Relevance 0
CN2 was found to contain two NH2-terminals (lysine and valine) and accounted for both of the cysteine residues of P2.
CN2 Binding (accounted) of
3) Confidence 0.14 Published 1980 Journal J. Neurochem. Section Abstract Doc Link 6161221 Disease Relevance 0 Pain Relevance 0.04
Lewis rats were immunized with P2 protein and peptides CN1, CN2 and CN3.
CN2 Binding (immunized) of
4) Confidence 0.10 Published 1983 Journal J. Neuroimmunol. Section Abstract Doc Link 6187769 Disease Relevance 0.16 Pain Relevance 0.07
Association of the peptidase inhibitor RB 101 and a CCK-B antagonist strongly enhances antinociceptive responses.
peptidase Binding (Association) of associated with analgesic, antagonist and antinociceptive
5) Confidence 0.04 Published 1993 Journal Neuroreport Section Title Doc Link 8369487 Disease Relevance 0 Pain Relevance 1.08

General Comments

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