INT41561

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Context Info
Confidence 0.07
First Reported 1981
Last Reported 1993
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 1.02
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
reticulum 1
Sis (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 1 97.76 Very High Very High Very High
Chronic pancreatitis 1 81.52 Quite High
Clonidine 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Pancreatitis 4 99.08 Very High Very High Very High
INFLAMMATION 1 97.76 Very High Very High Very High
Disorders Of Creatine Metabolism 3 95.64 Very High Very High Very High
Pancreatic Cancer 4 90.48 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
At high glucose, however, a partial inhibition of both insulin release (approximately 50%) and acid alpha-glucosidase activity was seen. 2-Deoxyglucose slightly suppressed acid phosphatase activity but did not influence the activities of neutral alpha-glucosidase or N-acetyl-beta-D- glucosaminidase.
Localization (release) of alpha-glucosidase
1) Confidence 0.07 Published 1993 Journal Pharmacology Section Abstract Doc Link 8441762 Disease Relevance 0 Pain Relevance 0.07
The activities of neutral alpha-glucosidase (endoplasmic reticulum) or acid phosphatase and N-acetyl-beta-D-glucosaminidase (lysosomes) were not affected by mannoheptulose. 2-Deoxyglucose (5 mmol/l), another glucose analogue, did not increase insulin secretion or acid alpha-glucosidase activity at low glucose.
Localization (secretion) of alpha-glucosidase in reticulum
2) Confidence 0.07 Published 1993 Journal Pharmacology Section Abstract Doc Link 8441762 Disease Relevance 0 Pain Relevance 0.07
Science renal enzyme excretion (alpha-glucosidase, gamma-glutamyltranspeptidase, leucine aminopeptidase) was not found to be invariably elevated when trypsin/creatinine clearance ratio was increased, tubular damage cannot be assumed as constituting the only reason for an altered clearance ratio.
Localization (excretion) of alpha-glucosidase associated with disorders of creatine metabolism
3) Confidence 0.02 Published 1981 Journal Gastroenterology Section Abstract Doc Link 6165644 Disease Relevance 1.02 Pain Relevance 0.13

General Comments

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