INT4187

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Context Info
Confidence 0.67
First Reported 1976
Last Reported 1985
Negated 3
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 1.16
Pain Relevance 0.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Glce)
Anatomy Link Frequency
renal medulla 1
papilla 1
Glce (Rattus norvegicus)
Pain Link Frequency Relevance Heat
medulla 10 98.00 Very High Very High Very High
aspirin 16 97.52 Very High Very High Very High
Analgesic 6 95.48 Very High Very High Very High
Disease Link Frequency Relevance Heat
Hyperbilirubinemia 2 99.76 Very High Very High Very High
Necrosis 4 98.96 Very High Very High Very High
Sprains And Strains 2 96.72 Very High Very High Very High
Renal Disease 4 95.96 Very High Very High Very High
Nephrotoxicity 2 75.00 Quite High
Hematuria 2 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Homozygous Gunn rats, mutant Wistars genetically lacking glucuronyl transferase, develop renal papillary necrosis after single oral doses of aspirin and of phenacetin.
Neg (lacking) Gene_expression (lacking) of glucuronyl transferase associated with aspirin and necrosis
1) Confidence 0.67 Published 1976 Journal J. Pathol. Section Abstract Doc Link 1003266 Disease Relevance 0.25 Pain Relevance 0.29
The homozygous Gunn rats have unconjugated hyperbilirubinemia due to the absence of glucuronyl transferase, leading to marked bilirubin deposition in renal medulla and papilla.
Neg (absence) Gene_expression (absence) of glucuronyl transferase in papilla associated with medulla and hyperbilirubinemia
2) Confidence 0.44 Published 1985 Journal Prostaglandins Section Abstract Doc Link 3864191 Disease Relevance 0.46 Pain Relevance 0.30
The homozygous Gunn rats have unconjugated hyperbilirubinemia due to the absence of glucuronyl transferase, leading to marked bilirubin deposition in renal medulla and papilla.
Neg (absence) Gene_expression (absence) of glucuronyl transferase in renal medulla associated with medulla and hyperbilirubinemia
3) Confidence 0.15 Published 1985 Journal Prostaglandins Section Abstract Doc Link 3864191 Disease Relevance 0.46 Pain Relevance 0.30

General Comments

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