INT41985

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Context Info
Confidence 0.44
First Reported 1984
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.60
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (HSD11B1) oxidoreductase activity (HSD11B1) endoplasmic reticulum (HSD11B1)
HSD11B1 (Homo sapiens)
Pain Link Frequency Relevance Heat
beta blocker 3 98.40 Very High Very High Very High
Clonidine 1 74.64 Quite High
Bile 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
alcohol 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 46 100.00 Very High Very High Very High
Hyperlipidemia 6 89.28 High High
Hypolipidemia 4 82.88 Quite High
Diabetes Mellitus 3 73.68 Quite High
Dyslipidemia /

Combined Dyslipidemia

6 69.36 Quite High
Fatty Liver 1 57.24 Quite High
Nash(non-alcoholic Steatohepatitis) 1 36.96 Quite Low
Prehypertension 4 13.28 Low Low
Hypertension 19 11.60 Low Low
Obesity 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A tendency for increased Tg levels and lower HDL-C concentrations was apparent during combined thiazide-type diuretic-beta-blocker treatment; these changes resembled those observed during beta-blocker monotherapy.
Regulation (apparent) of Regulation (tendency) of HDL associated with beta blocker and disorder of lipid metabolism
1) Confidence 0.44 Published 1984 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 6204152 Disease Relevance 0.27 Pain Relevance 0.17
However, changes on TC and HDL-C were dependent in TAG concentration, meanwhile LDL-C values decreased after treatment in an independent way.
Regulation (dependent) of Regulation (changes) of HDL associated with disorder of lipid metabolism
2) Confidence 0.26 Published 2007 Journal Lipids Health Dis Section Body Doc Link PMC2211748 Disease Relevance 1.26 Pain Relevance 0

General Comments

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