INT4207

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Context Info
Confidence 0.62
First Reported 1976
Last Reported 2010
Negated 63
Speculated 23
Reported most in Abstract
Documents 267
Total Number 292
Disease Relevance 63.72
Pain Relevance 115.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Avp) extracellular space (Avp) extracellular region (Avp)
response to stress (Avp) signal transducer activity (Avp)
Anatomy Link Frequency
plasma 44
nucleus 15
neurons 10
hypothalamus 8
pituitary 8
Avp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
narcan 367 100.00 Very High Very High Very High
antagonist 347 100.00 Very High Very High Very High
alcohol 205 100.00 Very High Very High Very High
agonist 187 100.00 Very High Very High Very High
Morphine 163 100.00 Very High Very High Very High
Opioid 153 100.00 Very High Very High Very High
cva 126 100.00 Very High Very High Very High
Pain 123 100.00 Very High Very High Very High
anesthesia 101 100.00 Very High Very High Very High
Enkephalin 92 100.00 Very High Very High Very High
Disease Link Frequency Relevance Heat
Stress 234 100.00 Very High Very High Very High
Pain 129 100.00 Very High Very High Very High
Injury 102 100.00 Very High Very High Very High
Natriuresis 97 100.00 Very High Very High Very High
Hemorrhage 83 100.00 Very High Very High Very High
Shock 61 100.00 Very High Very High Very High
Hypotension 24 100.00 Very High Very High Very High
Hypersensitivity 5 100.00 Very High Very High Very High
Hyponatremia 110 99.96 Very High Very High Very High
Diabetes Insipidus 40 99.88 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Effect of arginine vasopressin on acupuncture analgesia in the rat.
Regulation (Effect) of arginine vasopressin associated with narcan, acupuncture and analgesia
1) Confidence 0.62 Published 2009 Journal Peptides Section Title Doc Link 19022309 Disease Relevance 0.16 Pain Relevance 1.29
We examined the effect of acute hypotensive hemorrhage on corticotropin-releasing hormone (CRH) and arginine vasopressin (AVP) messenger RNAs (mRNAs) in neurons of the rat hypothalamus.
Spec (examined) Regulation (effect) of AVP in hypothalamus associated with hypotension and cva
2) Confidence 0.62 Published 1992 Journal Endocrinology Section Abstract Doc Link 1311234 Disease Relevance 0.58 Pain Relevance 0.32
These results indicate that in patients undergoing cardiac surgery the neuroendocrine reflex control of plasma AVP levels in relation to changes in arterial pressure is intact, but that the sensitivity of the reflex (i.e. the increase in plasma AVP level for a given fall in arterial pressure) is reduced by the administration of high doses of intravenous morphine.
Regulation (control) of AVP in plasma associated with morphine
3) Confidence 0.62 Published 1989 Journal Br J Surg Section Abstract Doc Link 2917257 Disease Relevance 0 Pain Relevance 0.44
The modification in the activity of noradrenergic neurons projecting to the hypothalamus and the pituitary-adrenal response during morphine withdrawal as well its correlation with alterations in corticotropin-releasing factor (CRF) and vasopressin (AVP) content in different brain areas was analyzed.
Regulation (alterations) of AVP in neurons associated with withdrawal and morphine
4) Confidence 0.61 Published 1998 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 9580616 Disease Relevance 0 Pain Relevance 0.47
The modification in the activity of noradrenergic neurons projecting to the hypothalamus and the pituitary-adrenal response during morphine withdrawal as well its correlation with alterations in corticotropin-releasing factor (CRF) and vasopressin (AVP) content in different brain areas was analyzed.
Regulation (alterations) of vasopressin in neurons associated with withdrawal and morphine
5) Confidence 0.61 Published 1998 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 9580616 Disease Relevance 0 Pain Relevance 0.47
Substance P did not modify and of these parameters in control rats, but elicited a marked pressor response, not associated with changes in heart rate or plasma vasopressin levels, in capsaicin-treated animals.
Neg (not) Regulation (changes) of vasopressin in plasma associated with qutenza and substance p
6) Confidence 0.61 Published 1983 Journal Neurosci. Lett. Section Abstract Doc Link 6200807 Disease Relevance 0 Pain Relevance 0.62
In contrast haloperidol did not affect the vasopressin response.
Regulation (affect) of vasopressin
7) Confidence 0.61 Published 1988 Journal J. Endocrinol. Section Abstract Doc Link 3351418 Disease Relevance 0 Pain Relevance 0.26
By comparison, mu and delta opioid agonists have little effect on vasopressin levels in water-deprived rats.
Neg (little) Regulation (effect) of vasopressin associated with mu agonist
8) Confidence 0.61 Published 1985 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 2991502 Disease Relevance 0.17 Pain Relevance 0.89
It should be noted that the lack of these two regulatory mechanisms controlling the level of circulating AVP greatly impairs the quantitative and dynamic predictions of this parameter and resulting ECF [Na+].


Regulation (controlling) of AVP
9) Confidence 0.61 Published 2010 Journal BMC Physiol Section Body Doc Link PMC2939538 Disease Relevance 0.16 Pain Relevance 0
However, RU 51599 did not show any effect on the AVP mRNA and AVP gene promoter activity stimulated by high osmolality and ET3.
Regulation (effect) of AVP
10) Confidence 0.60 Published 1997 Journal Neuropeptides Section Abstract Doc Link 9413018 Disease Relevance 0.32 Pain Relevance 0.13
However, RU 51599 did not show any effect on the AVP mRNA and AVP gene promoter activity stimulated by high osmolality and ET3.
Regulation (effect) of AVP mRNA
11) Confidence 0.60 Published 1997 Journal Neuropeptides Section Abstract Doc Link 9413018 Disease Relevance 0.32 Pain Relevance 0.13
These results indicate, therefore, that RU 51599 suppresses AVP secretion by inhibition at the step of AVP release during osmotic and non-osmotic stimulation but does not affect the AVP gene transcription level in the SCLC cells.
Neg (not) Regulation (affect) of AVP associated with small cell lung cancer
12) Confidence 0.60 Published 1997 Journal Neuropeptides Section Abstract Doc Link 9413018 Disease Relevance 0.39 Pain Relevance 0.07
The results indicated that AVP regulation of antinociception was limited to the brain nuclei.
Regulation (regulation) of AVP in brain associated with antinociception
13) Confidence 0.60 Published 2006 Journal Peptides Section Abstract Doc Link 17018240 Disease Relevance 0.52 Pain Relevance 0.72
The effects of restraint or hypertonic saline stress on corticotrophin-releasing factor, arginine vasopressin, and proenkephalin A mRNAs in the CFY, Sprague-Dawley and Wistar strains of rat.
Regulation (effects) of arginine vasopressin associated with stress, enkephalin and sprains and strains
14) Confidence 0.60 Published 1994 Journal Brain Res. Section Title Doc Link 7895084 Disease Relevance 1.08 Pain Relevance 0.10
Marked changes of arginine vasopressin, oxytocin, and corticotropin-releasing hormone in hypophysial portal plasma after pituitary stalk damage in the rat.
Regulation (changes) of arginine vasopressin in plasma
15) Confidence 0.60 Published 1995 Journal Endocrinology Section Title Doc Link 7720631 Disease Relevance 0.09 Pain Relevance 0.09
Plasma ANP and AVP, measured at 20 and 120 minutes after injection, were not altered by 2.5 and 25 microg [Dmt]DALDA.
Neg (not) Regulation (altered) of AVP in Plasma
16) Confidence 0.60 Published 2004 Journal J. Cardiovasc. Pharmacol. Section Abstract Doc Link 15550783 Disease Relevance 0.07 Pain Relevance 0.53
Effects of intracerebroventricular (third ventricle) injection of N-methyl-D-aspartate (NMDA) on arterial blood pressure, on heart rate, on arginine vasopressin (AVP) and levels of catecholamines in plasma and on the behaviour of normotensive freely-moving rats have been evaluated.
Regulation (Effects) of arginine vasopressin in plasma associated with catecholamine and intracerebroventricular
17) Confidence 0.60 Published 1992 Journal Neuropharmacology Section Abstract Doc Link 1355901 Disease Relevance 0.27 Pain Relevance 0.30
The effects of mu- and K-opiate receptor agonists on plasma concentrations of immunoreactive (ir) oxytocin (OXY) and arginine vasopressin (AVP) in normally hydrated and water-deprived rats were studied. 2.
Regulation (effects) of arginine vasopressin in plasma associated with agonist and opiate
18) Confidence 0.60 Published 1989 Journal Clin. Exp. Pharmacol. Physiol. Section Abstract Doc Link 2541954 Disease Relevance 0 Pain Relevance 0.34
Changes in plasma level of arginine vasopressin (AVP), arterial pressure, and urine flow were studied before, during and after cardiopulmonary bypass (CPB) in 11 patients with congenital heart disease.
Regulation (Changes) of AVP in urine associated with coronary heart disease
19) Confidence 0.59 Published 1989 Journal J. Korean Med. Sci. Section Abstract Doc Link 2597363 Disease Relevance 0.10 Pain Relevance 0.24
To assess the influence of vasopressin on splanchnic and renal circulatory changes induced by haemorrhage in portal hypertension, we studied 4 groups of 7 rats with chronic portal vein stenosis.
Regulation (influence) of vasopressin in portal vein associated with pressure and volume under development, pathologic constriction and cva
20) Confidence 0.59 Published 1986 Journal J. Hepatol. Section Abstract Doc Link 3722788 Disease Relevance 0.57 Pain Relevance 0.12

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