INT42099

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Context Info
Confidence 0.45
First Reported 1983
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.46
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (AKR1B1) carbohydrate metabolic process (AKR1B1) response to stress (AKR1B1)
cytoplasm (AKR1B1) cytosol (AKR1B1) extracellular space (AKR1B1)
AKR1B1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Painful diabetic neuropathy 2 99.08 Very High Very High Very High
Pain 3 88.64 High High
diabetic neuropathy 2 62.40 Quite High
Disease Link Frequency Relevance Heat
Diabetic Neuropathy 4 99.08 Very High Very High Very High
Neuropathy 2 97.84 Very High Very High Very High
Pain 3 88.64 High High
Diabetes Mellitus 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A controlled trial of sorbinil, an aldose reductase inhibitor, in chronic painful diabetic neuropathy.
Regulation (controlled) of aldose reductase associated with painful diabetic neuropathy
1) Confidence 0.45 Published 1983 Journal Diabetes Section Title Doc Link 6225686 Disease Relevance 0.36 Pain Relevance 0.39
OBJECTIVES: To assess the effects of aldose reductase inhibitors on the progression of symptoms, signs or functional disability in diabetic polyneuropathy.
Regulation (effects) of aldose reductase
2) Confidence 0.44 Published 2007 Journal Cochrane Database Syst Rev Section Body Doc Link 17943821 Disease Relevance 0.10 Pain Relevance 0

General Comments

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