INT42277

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Context Info
Confidence 0.25
First Reported 1980
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 2.06
Pain Relevance 1.61

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GIPC1) protein targeting (GIPC1) cytoplasmic membrane-bounded vesicle (GIPC1)
cytoplasm (GIPC1)
GIPC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
opioid receptor 2 98.68 Very High Very High Very High
chemokine 24 98.44 Very High Very High Very High
Pain 21 97.76 Very High Very High Very High
opiate 1 88.72 High High
cytokine 4 86.36 High High
abdominal pain 1 82.92 Quite High
antidepressant 1 79.04 Quite High
spastic colon 5 75.84 Quite High
agonist 5 74.08 Quite High
Lasting pain 4 72.80 Quite High
Disease Link Frequency Relevance Heat
Disease 35 99.40 Very High Very High Very High
Pain 21 97.76 Very High Very High Very High
Herpes Zoster 152 96.48 Very High Very High Very High
Cancer 103 90.88 High High
Abdominal Pain 1 82.92 Quite High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

3 75.84 Quite High
Metastasis 8 75.64 Quite High
Functional Bowel Disorder 2 75.64 Quite High
Breast Cancer 89 70.32 Quite High
Post Operative Pain 26 54.64 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The main findings were: (1) difficulties with social inhibition and dependency were associated with longer disease duration; (2) change in mean IIP-32 over 15 months was significantly correlated with changes in pain, but these relationships were mediated by change in psychological distress; (3) change in IIP-32 was an independent predictor of improved health status at 15 months only in the psychotherapy group.
Gene_expression (over) of IIP-32 associated with pain and disease
1) Confidence 0.25 Published 2009 Journal Pain Section Abstract Doc Link 19643544 Disease Relevance 0.50 Pain Relevance 0.64
We calculated that the anti-NIP trimerbody has at least a 100-fold increase in apparent functional affinity for NIP-BSA conjugates compared to its monovalent counterpart.
Gene_expression (has) of anti-NIP trimerbody
2) Confidence 0.14 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2670539 Disease Relevance 0.22 Pain Relevance 0
However, in case of introduction in the NIP, the CDC price of $107.67 or approximately €77 (January 2009) seems more applicable.
Gene_expression (introduction) of NIP
3) Confidence 0.06 Published 2010 Journal BMC Health Serv Res Section Body Doc Link PMC2928772 Disease Relevance 0.60 Pain Relevance 0.11
beta-endorphin: synthesis of analogs with extension at the carboxyl terminus with high radioreceptor binding activity.
Gene_expression (synthesis) of terminus
4) Confidence 0.06 Published 1980 Journal Int. J. Pept. Protein Res. Section Title Doc Link 6254896 Disease Relevance 0 Pain Relevance 0.09
Human mu-opioid receptor (HmuOR) with a tag of six consecutive histidines at its carboxyl terminus had been expressed in recombinant baculovirus infected Sf9 insect cells.
Gene_expression (expressed) of terminus associated with opioid receptor
5) Confidence 0.02 Published 2000 Journal Cell Res. Section Abstract Doc Link 10896171 Disease Relevance 0 Pain Relevance 0.50
The disparity in angiogenic activity among CXC chemokine family members is attributed to three amino acid structural domains at the N terminus, Glu-Leu-Arg (ELR), which is present in angiogenic (i.e., CXCL1, CXCL2, CXCL3, CXCL5, CXCL6, CXCL7, and CXCL8) [4-6], but not angiostatic (i.e., CXCL4, CXCL9, CXCL10, and CXCL11) CXC chemokines [7].
Gene_expression (present) of terminus associated with chemokine
6) Confidence 0.00 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2895614 Disease Relevance 0.59 Pain Relevance 0.27

General Comments

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