INT42278

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Context Info
Confidence 0.03
First Reported 1980
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.33
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GIPC1) protein targeting (GIPC1) cytoplasmic membrane-bounded vesicle (GIPC1)
cytoplasm (GIPC1)
Anatomy Link Frequency
Cleavage 1
GIPC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
opiate 1 90.36 High High
Inflammation 4 89.28 High High
agonist 3 80.84 Quite High
spinal inflammation 1 80.16 Quite High
Pain 2 42.32 Quite Low
antagonist 2 26.80 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 3 89.28 High High
Autoimmune Disease 1 81.68 Quite High
Low Back Pain 1 80.16 Quite High
Disease 3 75.00 Quite High
Injury 1 48.00 Quite Low
Pain 2 42.32 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
beta-endorphin: synthesis of analogs with extension at the carboxyl terminus with high radioreceptor binding activity.
terminus Binding (activity) of
1) Confidence 0.03 Published 1980 Journal Int. J. Pept. Protein Res. Section Title Doc Link 6254896 Disease Relevance 0 Pain Relevance 0.09
The F pocket of major histocompatibility complex (in humans HLA) class I molecules accommodates the C terminus of the bound peptide.
terminus Binding (bound) of
2) Confidence 0.01 Published 2005 Journal J. Mol. Biol. Section Abstract Doc Link 15713487 Disease Relevance 0.16 Pain Relevance 0.08
Cleavage within the extracellular amino terminus exposes a tethered ligand domain, which binds to and activates the receptors to initiate multiple signaling cascades.
terminus Binding (binds) of in Cleavage
3) Confidence 0.01 Published 2004 Journal Physiol. Rev. Section Abstract Doc Link 15044683 Disease Relevance 0.16 Pain Relevance 0.09

General Comments

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