INT42375

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.14
First Reported 1981
Last Reported 2008
Negated 0
Speculated 0
Reported most in Title
Documents 2
Total Number 2
Disease Relevance 0.10
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Pde5a) signal transduction (Pde5a)
Anatomy Link Frequency
medial vestibular nucleus 2
Pde5a (Mus musculus)
Pain Link Frequency Relevance Heat
potassium channel 1 98.12 Very High Very High Very High
sodium channel 1 85.20 High High
tetrodotoxin 4 72.88 Quite High
Somatosensory cortex 1 51.08 Quite High
agonist 6 46.96 Quite Low
Thalamus 3 40.24 Quite Low
GABAergic 15 14.24 Low Low
nMDA receptor 27 5.00 Very Low Very Low Very Low
Central nervous system 15 5.00 Very Low Very Low Very Low
long-term potentiation 13 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Ganglion Cysts 3 95.44 Very High Very High Very High
Depression 11 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 4 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low
Shock 2 5.00 Very Low Very Low Very Low
Stress 2 5.00 Very Low Very Low Very Low
Cv Unclassified Under Development 2 5.00 Very Low Very Low Very Low
Demyelinating Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Alternatively, CNG channel activation following NO-evoked cGMP accumulation may produce excitatory postsynaptic responses in central neurones, as was shown first in a population of retinal ganglion cells (Ahmad et al., 1994; Kawa & Sterling, 2002) and, more recently, in medial vestibular nucleus neurones (Podda et al., 2008), but the engagement of this pathway by endogenous NO has not yet been demonstrated.
Positive_regulation (activation) of Positive_regulation (accumulation) of cGMP in medial vestibular nucleus associated with ganglion cysts
1) Confidence 0.14 Published 2008 Journal The European Journal of Neuroscience Section Body Doc Link PMC2610389 Disease Relevance 0.10 Pain Relevance 0.03
Increase of cGMP and accumulation of 45Ca2+ evoked by drugs acting on sodium or potassium channels.
Positive_regulation (Increase) of Positive_regulation (accumulation) of cGMP associated with potassium channel
2) Confidence 0.05 Published 1981 Journal Eur. J. Pharmacol. Section Title Doc Link 6262096 Disease Relevance 0 Pain Relevance 0.16

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox