INT4238

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.58
First Reported 1976
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 7
Total Number 7
Disease Relevance 3.31
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (ALPI)
Anatomy Link Frequency
liver 1
foot 1
ALPI (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 27 99.90 Very High Very High Very High
Inflammatory marker 1 94.44 High High
Bile 3 56.20 Quite High
adenocard 1 10.84 Low Low
Bioavailability 7 5.00 Very Low Very Low Very Low
rheumatoid arthritis 6 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
backache 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Morphine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 21 99.90 Very High Very High Very High
Pressure And Volume Under Development 2 98.90 Very High Very High Very High
Congenital Anomalies 2 96.96 Very High Very High Very High
INFLAMMATION 4 94.16 High High
Liver Disease 1 93.60 High High
Osteoporosis 58 93.32 High High
Fatty Liver 1 92.56 High High
Bone Disease 3 84.52 Quite High
Melorheostosis 2 84.44 Quite High
Hypercalcemia 25 82.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pain and tenderness was greatly diminished and urinary hydroxyproline and serum alkaline phosphatase levels were significantly decreased.
Negative_regulation (decreased) of serum alkaline phosphatase associated with pain
1) Confidence 0.58 Published 1976 Journal Clin. Endocrinol. (Oxf) Section Abstract Doc Link 1052783 Disease Relevance 0.44 Pain Relevance 0.19
Chemotherapy with cyclophosphamide and 5-fluorouracil rendered the patient free of pain while reducing serum acid and alkaline phosphatase levels and restoring serum total and ionized calcium and urinary cyclic AMP excretion to normal.
Negative_regulation (reducing) of alkaline phosphatase associated with pain
2) Confidence 0.48 Published 1981 Journal Am. J. Med. Section Abstract Doc Link 7246580 Disease Relevance 0.93 Pain Relevance 0.16
Serum alkaline phosphatase decreased with nadir averages of 29.5% in females and 52.1% in males.
Negative_regulation (decreased) of Serum alkaline phosphatase
3) Confidence 0.39 Published 2005 Journal Clin. Cancer Res. Section Body Doc Link 15958630 Disease Relevance 0.19 Pain Relevance 0
Under either therapy satisfactory clinical and biological results have been observed (diminution of pain and decreased levels of serum alkaline phosphatase and hydroxyprolinuria).
Negative_regulation (decreased) of serum alkaline phosphatase associated with pain
4) Confidence 0.34 Published 1981 Journal Schweiz Med Wochenschr Section Abstract Doc Link 6785879 Disease Relevance 0.26 Pain Relevance 0.10
Following treatment with bisphosphonate (30 mg/day of pamidronate for 6 days) infusion, the pain and swelling of his right foot showed improvement and his elevated serum alkaline phosphatase decreased.
Negative_regulation (decreased) of serum alkaline phosphatase in foot associated with pain and pressure and volume under development
5) Confidence 0.34 Published 2002 Journal Skeletal Radiol. Section Abstract Doc Link 12483433 Disease Relevance 0.44 Pain Relevance 0.10
Cyclical etidronate treatment significantly increased the lumbar BMD compared with alfacalcidol by decreasing the serum alkaline phosphatase and osteocalcin and urinary hydroxyproline/creatinine and calcium/creatinine levels.
Negative_regulation (decreasing) of serum alkaline phosphatase
6) Confidence 0.04 Published 2005 Journal Yonsei Medical Journal Section Body Doc Link PMC2815806 Disease Relevance 0.66 Pain Relevance 0
Of importance, fenofibrate can significantly decrease serum uric acid levels by increasing renal urate expression, and considerable reductions in serum alkaline phosphatase and gamma glutamyltransferase activity are commonly observed during therapy with fenofibrate.63,68 The latter effects may have an application in patients with liver diseases, including nonalcoholic fatty liver disease.
Negative_regulation (reductions) of serum alkaline phosphatase in liver associated with fatty liver and liver disease
7) Confidence 0.04 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2922314 Disease Relevance 0.33 Pain Relevance 0.08

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox