INT42469

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.60
First Reported 1981
Last Reported 2011
Negated 2
Speculated 0
Reported most in Abstract
Documents 9
Total Number 9
Disease Relevance 0.46
Pain Relevance 0.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (LNPEP) peptidase activity (LNPEP) extracellular region (LNPEP)
plasma membrane (LNPEP) intracellular (LNPEP) cell-cell signaling (LNPEP)
LNPEP (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 1 96.56 Very High Very High Very High
Pain 1 94.12 High High
pain labor 1 92.08 High High
agonist 5 89.04 High High
Action potential 3 87.96 High High
Potency 2 80.00 Quite High
Neuropeptide 5 75.00 Quite High
aspirin 1 64.72 Quite High
Paracetamol 1 62.48 Quite High
Enkephalin 3 53.96 Quite High
Disease Link Frequency Relevance Heat
Obesity 1 96.48 Very High Very High Very High
Pain 1 94.12 High High
Deafness 1 92.16 High High
Labor Pain 1 92.08 High High
Reprotox - General 1 1 88.92 High High
Pre-term Labor 27 50.00 Quite Low
Cardiovascular Disorder Under Development 1 28.20 Quite Low
Hypertrophy 1 27.24 Quite Low
Hypertension 27 21.56 Low Low
Aging 2 7.84 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Transcriptional regulation of human placental leucine aminopeptidase/oxytocinase gene.
Regulation (regulation) of oxytocinase
1) Confidence 0.60 Published 2001 Journal Mol. Hum. Reprod. Section Title Doc Link 11517297 Disease Relevance 0.18 Pain Relevance 0.09
The rat homologue of human P-LAP is insulin-regulated aminopeptidase (IRAP) [57].
Regulation (regulated) of IRAP
2) Confidence 0.60 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC3005972 Disease Relevance 0.10 Pain Relevance 0
Angiotensin AT4 ligands are potent, competitive inhibitors of insulin regulated aminopeptidase (IRAP).
Regulation (regulated) of IRAP
3) Confidence 0.45 Published 2003 Journal J. Neurochem. Section Title Doc Link 12871575 Disease Relevance 0 Pain Relevance 0.05
Angiotensin AT4 ligands are potent, competitive inhibitors of insulin regulated aminopeptidase (IRAP).
Regulation (regulated) of insulin regulated aminopeptidase
4) Confidence 0.45 Published 2003 Journal J. Neurochem. Section Title Doc Link 12871575 Disease Relevance 0 Pain Relevance 0.05
Angiotensin AT4 ligands are potent, competitive inhibitors of insulin regulated aminopeptidase (IRAP).
Regulation (regulated) of insulin regulated aminopeptidase
5) Confidence 0.45 Published 2003 Journal J. Neurochem. Section Title Doc Link 12871575 Disease Relevance 0 Pain Relevance 0.05
While no significant changes of placental oxytocinase activities were found between these specimens.
Neg (no) Regulation (changes) of oxytocinase
6) Confidence 0.27 Published 1981 Journal Acta Obstet Gynaecol Jpn Section Abstract Doc Link 7211227 Disease Relevance 0.09 Pain Relevance 0.09
At the earliest ages examined, animals showed very insensitive CM and virtually no CAP responses.
Neg (no) Regulation (responses) of CAP
7) Confidence 0.26 Published 2007 Journal J. Comp. Physiol. A Neuroethol. Sens. Neural. Behav. Physiol. Section Abstract Doc Link 17323066 Disease Relevance 0.09 Pain Relevance 0.08
The effect of prostaglandins (PGs) and other compounds on human serum oxytocinase (EC 3.4.11.3) activity in vitro was studied by a sensitive assay using S-benzyl-L-cysteine-p-nitroanilide as substrate.
Regulation (effect) of oxytocinase
8) Confidence 0.26 Published 1981 Journal Prostaglandins Med Section Abstract Doc Link 6267639 Disease Relevance 0 Pain Relevance 0.13
Therefore, homodimerization is an important component in the regulation of the Y4 receptor.
Regulation (regulation) of Y4 receptor
9) Confidence 0.14 Published 2003 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 14551289 Disease Relevance 0 Pain Relevance 0.26

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox