INT42552

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Context Info
Confidence 0.14
First Reported 1981
Last Reported 1981
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.94

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lyase activity (Pck1) nucleolus (Pck1) nucleus (Pck1)
lipid metabolic process (Pck1) cytoplasm (Pck1)
Anatomy Link Frequency
caudate nucleus 2
Pck1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 1 98.10 Very High Very High Very High
opiate 3 97.68 Very High Very High Very High
Morphine 4 84.64 Quite High
fortral 1 80.28 Quite High
Enkephalin 2 78.40 Quite High
Potency 1 74.76 Quite High
Opioid 1 70.36 Quite High
narcan 1 69.24 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These results suggest that GTP plays an important role in the regulation of adenylate cyclase activity in the rat caudate nucleus and that the occupation of opiate receptor by agonists inhibits the enzyme through an actual increase in the inhibitory action of GTP, rather than a suppression of the enzymatic degradation of GTP.
Negative_regulation (suppression) of Protein_catabolism (degradation) of GTP in caudate nucleus associated with agonist and opiate
1) Confidence 0.14 Published 1981 Journal Jpn. J. Pharmacol. Section Abstract Doc Link 6273623 Disease Relevance 0 Pain Relevance 0.94

General Comments

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