INT42560

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Context Info
Confidence 0.50
First Reported 1981
Last Reported 1981
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.36
Pain Relevance 0.36

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cell differentiation (PGF) signal transduction (PGF) extracellular region (PGF)
plasma membrane (OXTR) cell-cell signaling (PGF) signal transducer activity (OXTR)
Anatomy Link Frequency
decidua 2
cervix 2
OXTR (Homo sapiens)
PGF (Homo sapiens)
Pain Link Frequency Relevance Heat
Dismenorea 4 99.28 Very High Very High Very High
Disease Link Frequency Relevance Heat
Dysmenorrhea 4 99.28 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We further suggest that the stimulation of PGF production by oxytocin is mediated by oxytocin receptors, probably in the decidua.
oxytocin Positive_regulation (stimulation) of Gene_expression (production) of PGF in decidua
1) Confidence 0.50 Published 1981 Journal Am. J. Obstet. Gynecol. Section Abstract Doc Link 6274193 Disease Relevance 0.17 Pain Relevance 0.17
We suggest that oxytocin stimulates PGF production in the pregnant uterus when it is appropriately sensitized to oxytocin, causing a potentiation of the oxytocin-induced contractions which is necessary for the contractions to become efficient in dilating the cervix.
oxytocin Positive_regulation (stimulates) of Gene_expression (production) of PGF in cervix
2) Confidence 0.39 Published 1981 Journal Am. J. Obstet. Gynecol. Section Abstract Doc Link 6274193 Disease Relevance 0.19 Pain Relevance 0.19

General Comments

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