INT42728

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Context Info
Confidence 0.00
First Reported 1982
Last Reported 1982
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 2.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (PRLR, Cpe) peptidase activity (Cpe) extracellular space (Cpe)
Golgi apparatus (Cpe) plasma membrane (PRLR)
PRLR (Homo sapiens)
Cpe (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 12 100.00 Very High Very High Very High
agonist 1 99.68 Very High Very High Very High
analgesia 8 99.64 Very High Very High Very High
antagonist 1 97.16 Very High Very High Very High
Opioid 5 93.92 High High
Morphine 3 89.48 High High
Analgesic 6 85.80 High High
Potency 2 77.08 Quite High
tail-flick 1 63.20 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using the enkephalins as the prototypic delta ligands (100 fold selective) and based on their effects on analgesia, we suggest that Leu-enkephalin-like peptides interact with the delta receptor as an "agonist" to facilitate and met-enkephalin-like peptides as an "antagonist" to attenuate analgesia.
delta receptor Binding (interact) of Leu-enkephalin associated with antagonist, agonist, enkephalin and analgesia
1) Confidence 0.00 Published 1982 Journal Life Sci. Section Abstract Doc Link 6283293 Disease Relevance 0 Pain Relevance 2.91

General Comments

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