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Context Info
Confidence 0.06
First Reported 1981
Last Reported 2002
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0.86

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cell death (PDYN) extracellular region (PDYN) plasma membrane (PDYN)
PDYN (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 11 100.00 Very High Very High Very High
Bioavailability 1 81.20 Quite High
Cholecystokinin 1 75.00 Quite High


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the presence of aminopeptidase inhibitors, amastatin, sodium deoxycholate and EDTA, the degradation of Leu-enkephalin was dramatically reduced.
Negative_regulation (reduced) of Protein_catabolism (degradation) of Leu-enkephalin associated with enkephalin
1) Confidence 0.06 Published 2002 Journal Int J Pharm Section Abstract Doc Link 11897418 Disease Relevance 0 Pain Relevance 0.31
The degradation of leu-enkephalin was inhibited in a dose-dependent manner by the presence of CCK-related peptides in the medium.
Negative_regulation (inhibited) of Protein_catabolism (degradation) of leu-enkephalin associated with enkephalin
2) Confidence 0.04 Published 1981 Journal Peptides Section Abstract Doc Link 6283489 Disease Relevance 0 Pain Relevance 0.55

General Comments

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