INT43131

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.36
First Reported 1982
Last Reported 2008
Negated 1
Speculated 0
Reported most in Abstract
Documents 3
Total Number 7
Disease Relevance 1.09
Pain Relevance 0.98

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (FOXC1) nucleus (FOXC1) DNA binding (FOXC1)
transcription factor binding (FOXC1) cytoplasm (FOXC1)
Anatomy Link Frequency
neurons 1
FOXC1 (Homo sapiens)
Pain Link Frequency Relevance Heat
dorsal root ganglion 1 100.00 Very High Very High Very High
midbrain 15 95.44 Very High Very High Very High
cerebral cortex 50 94.92 High High
Thalamus 35 94.92 High High
qutenza 3 94.44 High High
Neuropathic pain 1 93.04 High High
Pain 1 92.72 High High
amygdala 5 87.84 High High
headache 1 87.20 High High
Central nervous system 5 85.00 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 1 99.52 Very High Very High Very High
Meningitis 4 99.16 Very High Very High Very High
Broca Aphasia 1 98.76 Very High Very High Very High
Toxicity 1 97.08 Very High Very High Very High
Non-diabetic Peripheral Neuropathy 1 93.16 High High
Neuropathic Pain 1 93.04 High High
Leukemia 1 90.04 High High
Vomiting 1 87.72 High High
Headache 1 87.20 High High
Disease 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Influence of treatments on CNS DHA and ARA
Regulation (Influence) of ARA
1) Confidence 0.36 Published 2005 Journal BMC Med Section Body Doc Link PMC1184078 Disease Relevance 0 Pain Relevance 0.10
Our experience suggests that ara-A is effective in the treatment of HSE if given early enough.
Regulation (effective) of ara associated with meningitis
2) Confidence 0.26 Published 1982 Journal Brain Dev. Section Abstract Doc Link 6301304 Disease Relevance 0.71 Pain Relevance 0.09
The influence of our treatments on CNS ARA concentrations is radically different from that for DHA.
Regulation (influence) of CNS ARA
3) Confidence 0.26 Published 2005 Journal BMC Med Section Body Doc Link PMC1184078 Disease Relevance 0 Pain Relevance 0
We studied the effects of Ara C on human dorsal root ganglion (DRG) neurons, especially the expression and sensitivity of the ion channel TRPV1, which responds to noxious heat and capsaicin and is a key mediator of neuropathic pain.
Regulation (effects) of Ara in neurons associated with ganglion cysts, dorsal root ganglion, qutenza and neuropathic pain
4) Confidence 0.24 Published 2008 Journal J. Neurooncol. Section Abstract Doc Link 18414789 Disease Relevance 0.38 Pain Relevance 0.41
ARA is much less sensitive to dietary manipulation than DHA, and the response of CNS regions to ARA supplementation is complex.
Regulation (sensitive) of ARA
5) Confidence 0.16 Published 2005 Journal BMC Med Section Body Doc Link PMC1184078 Disease Relevance 0 Pain Relevance 0.05
We quantitatively mapped fatty acids in 26 regions of the four-week-old breastfed baboon CNS, and studied the influence of dietary DHA and ARA supplementation and prematurity on CNS DHA and ARA concentrations.


Regulation (concentrations) of ARA
6) Confidence 0.16 Published 2005 Journal BMC Med Section Abstract Doc Link PMC1184078 Disease Relevance 0 Pain Relevance 0.14
Dietary supplementation increased DHA in all structures but had little influence on ARA concentrations.
Neg (little) Regulation (influence) of ARA
7) Confidence 0.16 Published 2005 Journal BMC Med Section Abstract Doc Link PMC1184078 Disease Relevance 0 Pain Relevance 0.20

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox