INT43165

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Context Info
Confidence 0.27
First Reported 1980
Last Reported 1995
Negated 0
Speculated 0
Reported most in Title
Documents 3
Total Number 3
Disease Relevance 0.10
Pain Relevance 1.86

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Gnrhr) signal transducer activity (Gnrhr)
Anatomy Link Frequency
thyroid 2
Gnrhr (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Clonidine 5 100.00 Very High Very High Very High
narcan 4 100.00 Very High Very High Very High
Pain 2 100.00 Very High Very High Very High
Acupuncture 2 100.00 Very High Very High Very High
analgesia 1 100.00 Very High Very High Very High
nMDA receptor 4 99.82 Very High Very High Very High
Enkephalin 8 96.32 Very High Very High Very High
opiate 6 95.60 Very High Very High Very High
nMDA receptor antagonist 1 93.48 High High
Central nervous system 1 92.40 High High
Disease Link Frequency Relevance Heat
Pain 1 100.00 Very High Very High Very High
Disease 1 25.00 Low Low
Carcinoid 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The NMDA receptor complex modulates clonidine-induced increases in growth hormone levels in rats.
Regulation (modulates) of Positive_regulation (increases) of growth hormone associated with nmda receptor and clonidine
1) Confidence 0.27 Published 1995 Journal Pharmacol. Biochem. Behav. Section Title Doc Link 7740072 Disease Relevance 0 Pain Relevance 0.70
The effect of naloxone on psychotropic drug-induced prolactin, growth hormone and cortisol secretion--a preliminary report.
Regulation (effect) of Positive_regulation (drug-induced) of growth hormone associated with narcan
2) Confidence 0.16 Published 1980 Journal Postgrad Med J Section Title Doc Link 7393831 Disease Relevance 0 Pain Relevance 0.32
Classical mu-receptors probably have beta-endorphin as an endogenous ligand, and seem to be involved in the modulation of pain perception, low-frequency acupuncture analgesia, and the stimulation of prolactin, growth hormone and thyroid-stimulating hormone release.
Regulation (modulation) of Positive_regulation (stimulation) of growth hormone in thyroid associated with pain, acupuncture and analgesia
3) Confidence 0.01 Published 1983 Journal Clin Endocrinol Metab Section Abstract Doc Link 6303648 Disease Relevance 0.10 Pain Relevance 0.83

General Comments

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